Casein Kinase 1 delta: Small Molecules and Peptides
Casein kinases are a group of ubiquitous Ser/Thr kinases that phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N- and C-terminal domains. The C-termini of the CK1 gamma isoforms carry putative palmitoylation sites. CK2 is a tetrameric kinase comprised of two catalytic subunits (CK2 alpha and/or CK2 alpha‘) and two identical regulatory subunits (CK2 beta).
8 results for "Casein Kinase 1 delta Small Molecules and Peptides" in Products
8 results for "Casein Kinase 1 delta Small Molecules and Peptides" in Products
Casein Kinase 1 delta: Small Molecules and Peptides
Casein kinases are a group of ubiquitous Ser/Thr kinases that phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N- and C-terminal domains. The C-termini of the CK1 gamma isoforms carry putative palmitoylation sites. CK2 is a tetrameric kinase comprised of two catalytic subunits (CK2 alpha and/or CK2 alpha‘) and two identical regulatory subunits (CK2 beta).
Selective inhibitor of p38 MAPK
| Chemical Name: | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine |
| Purity: | ≥98% (HPLC) |
Selective inhibitor of p38 MAPK; water-soluble
| Chemical Name: | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulphonyl)phenyl]-1H-imidazol-4-yl]pyridine hydrochloride |
| Purity: | ≥98% (HPLC) |
CK1 inhibitor
| Chemical Name: | N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride |
| Purity: | ≥99% (HPLC) |
Potent and selective CK1ε and CK1δ inhibitor
| Chemical Name: | 4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent CK1 inhibitor; also inhibits cyclin-dependent kinases
| Chemical Name: | 2-[[9-(1-Methylethyl)-6-[[3-(2-pyridinyl)phenyl]amino]-9H-purin-2-yl]amino]-1-butanol dihydrochloride |
| Purity: | ≥98% (HPLC) |
Selective CK1 inhibitor. Also inhibits TGF-βRI
| Chemical Name: | 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Purity: | ≥98% (HPLC) |
Potent and selective CK1α, CK1δ and CK1ε inhibitor
| Chemical Name: | 4-(1-((4-Fluoro-1-methylpiperidin-4-yl)methyl)-4-(5-fluoropyridin-2-yl)-1H-imidazol-5-yl)-1H-pyrrolo[2,3-b]pyridine |
| Purity: | ≥98% (HPLC) |
Potent CK1δ/ε inhibitor
| Chemical Name: | 4-[4-(4-Fluorophenyl)-1-[1-(3-isoxazolylmethyl)-4-piperidinyl]-1H-imidazol-5-yl]-2-pyrimidinamine |
| Purity: | ≥98% (HPLC) |
