CKI 7 dihydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 5329

CK1 inhibitor
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Key Product Details

Description

CK1 inhibitor

View all Casein Kinase 1 Inhibitors »

Product Description

CKI 7 dihydrochloride is a casein kinase 1 (CK1) inhibitor. Also inhibits SGK, S6K1 and MSK1. Induces retinal cell differentiation from human ESCs and iPSCs in combination with SB 431542 (Cat. No. 1614) and Y-27632 (Cat. No. 1254).

Product Specifications

Molecular Weight

358.67

Formula

C11H12ClN3O2S.2HCl

Storage

Store at -20°C

Purity

≥99% (HPLC)

Chemical Name

N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride

CAS Number

1177141-67-1

PubChem ID

16078955

InChI Key

JUAVTXYOCISSSL-UHFFFAOYSA-N

SMILES

ClC2=CC=C(S(NCCN)(=O)=O)C1=CN=CC=C12.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 3.59 10
DMSO 17.93 50

Preparing Stock Solutions for CKI 7 dihydrochloride

The following data is based on the product molecular weight 358.67

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 5.58 mL 27.88 mL 55.76 mL
2.5 mM 1.12 mL 5.58 mL 11.15 mL
5 mM 0.56 mL 2.79 mL 5.58 mL
25 mM 0.11 mL 0.56 mL 1.12 mL

Calculators

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Reconstitution Calculator

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Product Documents for CKI 7 dihydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CKI 7 dihydrochloride

For research use only

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