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8 results for "CHRM2 Small Molecules and Peptides" in Products

CHRM2: Small Molecules and Peptides

Muscarinic receptors are G protein-coupled receptors that mediate the response to acetylcholine released from parasympathetic nerves. Their role in the unconscious regulation of organ and central nervous system function makes them potential therapeutic targets for a broad spectrum of diseases. CHRM2 is of particular interest because of its extensive pharmacological characterization with both orthosteric and allosteric ligands.

Selective M2 antagonist

Chemical Name: N,N-Dimethyl-3-[(1S)-1-(2-pyridinyl)ethyl]-1H-indene-2-ethanamine maleate
Purity: ≥98% (HPLC)
Selective M2 antagonist

Selective M2 antagonist

Alternate Names: Otenzepad
Chemical Name: 11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Purity: ≥98% (HPLC)
Selective M2 antagonist

Muscarinic agonist

Chemical Name: (3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride
Purity: ≥98% (HPLC)
Muscarinic agonist

Muscarinic agonist

Chemical Name: 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone sesquifumarate
Purity: ≥98% (HPLC)
Muscarinic agonist

Potent M2/M4 antagonist

Chemical Name: N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide
Purity: ≥98% (HPLC)
Potent M2/M4 antagonist

Selective M1 muscarinic agonist

Chemical Name: 4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium chloride
Purity: ≥99% (HPLC)
Selective M1 muscarinic agonist

Positive allosteric modulator of M2 and M4 receptors

Chemical Name: 3-Amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methyl-1-piperazinyl)-2-oxoethoxy]-thieno[2,3-b]pyridine-2-carboxamide
Purity: ≥98% (HPLC)
Positive allosteric modulator of M2 and M4 receptors

High affinity and selective M2 antagonist

Chemical Name: 11-[[4-[4-(Diethylamino)butyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Purity: ≥98% (HPLC)
High affinity and selective M2 antagonist
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