Pilocarpine hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0694
Muscarinic agonist
Product Description
Pilocarpine hydrochloride is an M3 muscarinic acetycholine receptor agonist.Product Specifications
Molecular Weight
244.72
Formula
C11H16N2O2.HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
(3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride
CAS Number
54-71-7
PubChem ID
5909
InChI Key
RNAICSBVACLLGM-GNAZCLTHSA-N
SMILES
O=C1[C@@]([H])(CC)[C@](CC2=CN=CN2C)([H])CO1.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 24.47 | 100 | |
| DMSO | 18.35 | 75 |
Preparing Stock Solutions
for Pilocarpine hydrochloride
The following data is based on the product molecular weight 244.72
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.09 mL | 20.43 mL | 40.86 mL |
| 5 mM | 0.82 mL | 4.09 mL | 8.17 mL |
| 10 mM | 0.41 mL | 2.04 mL | 4.09 mL |
| 50 mM | 0.08 mL | 0.41 mL | 0.82 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Wang PilC modulates the cellular electrical properties of mammalian hearts by activating a cardiac M3 receptor and a K+ current. Br.J.Pharmacol. 1999 PMID: 10372814
- Brown and Taylor Muscarinic receptor agonists and antagonists. The Pharmacological Basis of Therapeutics. Eds Goo
- ten Berge Differences in the prejunctional effects of methach. and PilC on the release of endogenous acetylcholine from guinea-pig trachea. Naunyn Schmiedebergs Arch.Pharmacol. 1996 PMID: 8938659
Product Specific Notices for Pilocarpine hydrochloride
For research use only
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