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Chemokine Receptor Antagonists: Small Molecules and Peptides

28 results for "Chemokine Receptor Antagonists Small Molecules and Peptides" in Products

28 results for "Chemokine Receptor Antagonists Small Molecules and Peptides" in Products

Chemokine Receptor Antagonists: Small Molecules and Peptides

Highly selective CCR2 chemokine receptor antagonist

Chemical Name: 6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one
Purity: ≥98% (HPLC)
Highly selective CCR2 chemokine receptor antagonist

CCR2b chemokine receptor antagonist

Chemical Name: 1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride
Purity: ≥98% (HPLC)
CCR2b chemokine receptor antagonist

Potent CCR1 chemokine receptor antagonist

Chemical Name: 1,4-cis-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidinium iodide
Purity: ≥98% (HPLC)
Potent CCR1 chemokine receptor antagonist

Potent and selective CCR5 and CCR2 chemokine receptor antagonist

Chemical Name: N-[[4-[[[6,7-Dihydro-2-(4-methylphenyl)-5H-benzocyclohepten-8-yl]carbonyl]amino]phenyl]methyl]tetrahydro-N,N-dimethyl-2H-pyran-4-aminium chloride
Purity: ≥98% (HPLC)
Potent and selective CCR5 and CCR2 chemokine receptor antagonist

Selective CCR5 antagonist

Alternate Names: UK-427857
Chemical Name: 4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl- 5-methyl-4H-1,2,4-triazol-4-yl)- 8-azabicyclo[3.2.1]oct-8-yl]-1- phenylpropyl}cyclohexanecarboxamide
Purity: ≥98% (HPLC)
Selective CCR5 antagonist

Highly selective CXCR4 antagonist

Alternate Names: JM 3100,Plerixafor
Chemical Name: 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride
Highly selective CXCR4 antagonist

Potent and selective CXCR2 antagonist

Chemical Name: N-(2-Bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)urea
Purity: ≥98% (HPLC)
Potent and selective CXCR2 antagonist

Potent, selective CCR1 antagonist

Alternate Names: ZK-811752
Chemical Name: (2R)-1-[[2-[(Aminocarbonyl)amino]-4-chlorophenoxy]acetyl]-4-[(4-fluorophenyl)methyl]-2-methylpiperazine
Purity: ≥98% (HPLC)
Potent, selective CCR1 antagonist

CXCR3 antagonist; inhibits cell migration and metastasis

Chemical Name: N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide
Purity: ≥98% (HPLC)
CXCR3 antagonist; inhibits cell migration and metastasis

Potent and selective CCR3 antagonist

Chemical Name: N-(1-Naphthalenylcarbonyl)-4-nitro-L-phenylalanine methyl ester
Purity: ≥98% (HPLC)
Potent and selective CCR3 antagonist

Potent and selective CCR4 antagonist

Chemical Name: 2,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide
Purity: ≥98% (HPLC)
Potent and selective CCR4 antagonist

Potent and selective hCXCR6 antagonist

Chemical Name: N-[(1R,3S,5S)-9-(2-((2-Chlorophenyl)amino)-2-exoethyl)-9-azabicyclo[3.3.1]nonan-3-yl)-3,4,5-trimethoxybenzamide
Purity: ≥98% (HPLC)
Potent and selective hCXCR6 antagonist

Potent CXCR2 antagonist

Chemical Name: N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea
Purity: ≥98% (HPLC)
Potent CXCR2 antagonist

High affinity, potent CCR2 antagonist

Chemical Name: 2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide
Purity: ≥98% (HPLC)
High affinity, potent CCR2 antagonist

Potent and selective CXCR4 antagonist

Chemical Name: N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide
Purity: ≥97% (HPLC)
Potent and selective CXCR4 antagonist

Potent and selective CXCR3 antagonist

Chemical Name: N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)benzeneacetamide
Purity: ≥98% (HPLC)
Potent and selective CXCR3 antagonist

Potent CXCR2 antagonist

Chemical Name: 5-[[(3-Chloro-2-fluorophenyl)methyl]thio]-7-[[(1R)-2-hydroxy-1-methylethyl]amino]thiazolo[4,5-d]pyrimidin-2(3H)-one
Purity: ≥98% (HPLC)
Potent CXCR2 antagonist

CX3CR1 antagonist

Chemical Name: 5-[3-[4-(4-Chlorophenyl)-1-piperidinyl]propyl]pyrrolo[1,2-a]quinoxalin-4(5H)-one hydrochloride
Purity: ≥98% (HPLC)
CX3CR1 antagonist

CXCR4 antagonist; antitumor

Purity: ≥95% (HPLC)
CXCR4 antagonist; antitumor

Potent CCR1 and CCR3 antagonist

Chemical Name: 1,4-trans-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidinium iodide
Purity: ≥98% (HPLC)
Potent CCR1 and CCR3 antagonist

Selective CCR1 antagonist

Alternate Names: VUF 2274
Chemical Name: 4-(4-Chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinepentanenitrile hydrochloride
Purity: ≥98% (HPLC)
Selective CCR1 antagonist

Potent CXCR2 antagonist

Chemical Name: 6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide
Purity: ≥98% (HPLC)
Potent CXCR2 antagonist

Potent CCR4 antagonist

Chemical Name: 2-[1,4'-Bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride
Purity: ≥98% (HPLC)
Potent CCR4 antagonist

Potent CCR4 antagonist

Chemical Name: N-[[3-[[3-[[(5-Chloro-2-thienyl)sulfonyl]amino]-4-methoxy-1H-indazol-1-yl]methyl]phenyl]methyl]-2-hydroxy-2-methylpropanamide
Purity: ≥98% (HPLC)
Potent CCR4 antagonist

Potent CXCR4 antagonist

Chemical Name: N,N'-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochloride
Purity: ≥98% (HPLC)
Potent CXCR4 antagonist
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