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Buffers, Chelators and Reagents: Small Molecules and Peptides

26 results for "Buffers, Chelators and Reagents Small Molecules and Peptides" in Products

26 results for "Buffers, Chelators and Reagents Small Molecules and Peptides" in Products

Buffers, Chelators and Reagents: Small Molecules and Peptides

Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist

Chemical Name: 2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate tri(triethylammonium) salt
Purity: ≥95% (HPLC)
Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist

Cell-permeable Ca2+ chelator

Chemical Name: 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester)
Purity: ≥95% (HPLC)
Cell-permeable Ca2+ chelator

Iron chelator; also hypoxia mimetic and neuroprotectant

Chemical Name: N4-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-(5-aminopentyl)-N1-hydroxybutanediamide methanesulfonate
Iron chelator; also hypoxia mimetic and neuroprotectant

Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor

Chemical Name: 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid disodium salt
Purity: ≥95% (HPLC)
Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor

Cell-permeable Zn2+ chelator; also inhibits RNA binding protein Lin28

Chemical Name: N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine
Purity: ≥97% (HPLC)
Cell-permeable Zn2+ chelator; also inhibits RNA binding protein Lin28

Forms monovalent ion channels in lipid bilyers; antifungal

Chemical Name: (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-Amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
Purity: ≥90% (HPLC)
Forms monovalent ion channels in lipid bilyers; antifungal

NHS ester hapten for labeling amino groups

Chemical Name: (3β,5β,12β)-3-[2-[[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]amino]-2-oxoethoxy]-12,14-dihydroxycard-20(22)-enolide
Purity: ≥80% (HPLC)
NHS ester hapten for labeling amino groups

PreQ1 with biotin handle for RNA labeling and purification

Chemical Name: N-(6-(((2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)amino)hexyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
Purity: ≥95% (HPLC)
PreQ1 with biotin handle for RNA labeling and purification
(3)

Antibiotic

Purity: ≥90% (HPLC)
Antibiotic

Reagent for synthetic biology; converts cysteine to dehydroalanine

Chemical Name: 2,5-Dibromohexanediamide
Reagent for synthetic biology; converts cysteine to dehydroalanine

Cationic ionizable lipid

Chemical Name: 1-Octylnonyl 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]octanoate
Purity: ≥95% (HPLC)
Cationic ionizable lipid

Chemoproteomic reagent, binds with reactive cysteines and labels with desthiobiotin

Chemical Name: (4R,5S)-N-[2-[(2-Iodoacetyl)amino]ethyl]-5-methyl-2-oxo-4-imidazolidinehexanamide
Purity: ≥95% (HPLC)
Chemoproteomic reagent, binds with reactive cysteines and labels with desthiobiotin

Cyclic complexing agent

Purity: ≥98% (HPLC)
Cyclic complexing agent

Synthetic thymidine analog; used for cell proliferation assays

Chemical Name: 5-Bromo-2-deoxyuridine
Purity: ≥98% (HPLC)
Synthetic thymidine analog; used for cell proliferation assays

Orally bioavailable prodrug metabolite, undergoes hydrolytic conversion to yield (S)-lactate and (R)-1,3-butanediol in cells

Chemical Name: (3R)-3-Hydroxybutyl (2S)-2-hydroxypropanoate and (1R)-3-Hydroxy-1-methylpropyl (2S)-2-hydroxypropanoate
Purity: ≥95%
Orally bioavailable prodrug metabolite, undergoes hydrolytic conversion to yield (S)-lactate and (R)-1,3-butanediol in cells

preQ1 with alkyne handle for click chemistry

Chemical Name: N-[6-[[(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]amino]hexyl]-3-(2-propyn-1-yloxy)propanamide
Purity: ≥95% (HPLC)
preQ1 with alkyne handle for click chemistry

Molecular glue; pre-mRNA splicing modulator

Chemical Name: N1-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide
Purity: ≥98% (HPLC)
Molecular glue; pre-mRNA splicing modulator

Metabolite

Chemical Name: (RS)-2-Hydroxypentanedioic acid disodium salt
Metabolite

DC-SIGN ligand used to target dendritic cells

Chemical Name: N-(4-(((2R,3S,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenethyl)pent-4-ynamide
Purity: ≥98% (HPLC)
DC-SIGN ligand used to target dendritic cells.

Ionizable cationic lipid

Chemical Name: 2-[2,2-Di-[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine
Purity: ≥95% (HPLC)
Ionizable cationic lipid

preQ1 with azide handle for click chemistry

Chemical Name: N-[6-[[(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]amino]hexyl]-3-(2-azidoethoxy)propanamide
Purity: ≥95% (HPLC)
preQ1 with azide handle for click chemistry

pan-DUB activity-based probe with alkyne click handle

Chemical Name: 4-(1-Cyanopyrrolidine-3-carbonyl)-N-[(4-ethynylphenyl)methyl]-1-methylpyrrole-2-carboxamide
Purity: ≥98% (HPLC)
pan-DUB activity-based probe with alkyne click handle

Broad spectrum cysteine reactive probe; suitable for live-cell applications

Alternate Names: N-Acryloylindole-alkyne,NAIA-5
Chemical Name: N-5-Hexyn-1-yl-2-[[1-(1-oxo-2-propen-1-yl)-1H-indol-5-yl]oxy]acetamide
Purity: ≥95% (HPLC)
Application of NAIA in HepG2 cells.
(4)

Heterobifunctional compound for nuclear import of FKBPF36V tagged proteins

Chemical Name: (R)-1-(3-((14-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2,13-dioxo-6,9-dioxa-3,12-diazatetradecyl)oxy)phenyl)-3-(3,4-dimethoxyphenyl)propyl (S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate
Purity: ≥98% (HPLC)
Heterobifunctional compound for nuclear import of PKBP F36V tagged proteins

Photosensitizer for proximity labeling experiments, NHS reactive group

Chemical Name: N-(2-(2-((6-Chlorohexyl)oxy)ethoxy)ethyl)-2-(10-methyl-2,4-dioxo-4,10-dihydropyrimido[4,5-b]quinolin-3(2H)-yl)acetamide
Purity: ≥95% (HPLC)
Photosensitizer for proximity labeling experiments, NHS reactive group
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