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26 results for "Buffers, Chelators and Reagents Small Molecules and Peptides" in Products

Buffers, Chelators and Reagents: Small Molecules and Peptides

Cell-permeable Zn2+ chelator; also inhibits RNA binding protein Lin28

Chemical Name: N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine
Purity: ≥97% (HPLC)
Cell-permeable Zn2+ chelator; also inhibits RNA binding protein Lin28

Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist

Chemical Name: 2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate tri(triethylammonium) salt
Purity: ≥95% (HPLC)
Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist

Iron chelator; also hypoxia mimetic and neuroprotectant

Chemical Name: N4-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-(5-aminopentyl)-N1-hydroxybutanediamide methanesulfonate
Iron chelator; also hypoxia mimetic and neuroprotectant

Cell-permeable Ca2+ chelator

Chemical Name: 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester)
Purity: ≥95% (HPLC)
Cell-permeable Ca2+ chelator

Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor

Chemical Name: 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid disodium salt
Purity: ≥95% (HPLC)
Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor

Cationic ionizable lipid

Chemical Name: 1-Octylnonyl 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]octanoate
Purity: ≥95% (HPLC)
Cationic ionizable lipid

Chemoproteomic reagent, binds with reactive cysteines and labels with desthiobiotin

Chemical Name: (4R,5S)-N-[2-[(2-Iodoacetyl)amino]ethyl]-5-methyl-2-oxo-4-imidazolidinehexanamide
Purity: ≥95% (HPLC)
Chemoproteomic reagent, binds with reactive cysteines and labels with desthiobiotin

Synthetic thymidine analog; used for cell proliferation assays

Chemical Name: 5-Bromo-2-deoxyuridine
Purity: ≥98% (HPLC)
Synthetic thymidine analog; used for cell proliferation assays

Reagent for synthetic biology; converts cysteine to dehydroalanine

Chemical Name: 2,5-Dibromohexanediamide
Reagent for synthetic biology; converts cysteine to dehydroalanine

Molecular glue; pre-mRNA splicing modulator

Chemical Name: N1-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide
Purity: ≥98% (HPLC)
Molecular glue; pre-mRNA splicing modulator

Cyclic complexing agent

Purity: ≥98% (HPLC)
Cyclic complexing agent

Metabolite

Chemical Name: (RS)-2-Hydroxypentanedioic acid disodium salt
Metabolite

NHS ester hapten for labeling amino groups

Chemical Name: (3β,5β,12β)-3-[2-[[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]amino]-2-oxoethoxy]-12,14-dihydroxycard-20(22)-enolide
Purity: ≥80% (HPLC)
NHS ester hapten for labeling amino groups

preQ1 with azide handle for click chemistry

Chemical Name: N-[6-[[(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]amino]hexyl]-3-(2-azidoethoxy)propanamide
Purity: ≥95% (HPLC)
preQ1 with azide handle for click chemistry

Heterobifunctional compound for nuclear import of FKBPF36V tagged proteins

Chemical Name: (R)-1-(3-((14-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2,13-dioxo-6,9-dioxa-3,12-diazatetradecyl)oxy)phenyl)-3-(3,4-dimethoxyphenyl)propyl (S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate
Purity: ≥98% (HPLC)
Heterobifunctional compound for nuclear import of PKBP F36V tagged proteins

Orally bioavailable prodrug metabolite, undergoes hydrolytic conversion to yield (S)-lactate and (R)-1,3-butanediol in cells

Chemical Name: (3R)-3-Hydroxybutyl (2S)-2-hydroxypropanoate and (1R)-3-Hydroxy-1-methylpropyl (2S)-2-hydroxypropanoate
Purity: ≥95%
Orally bioavailable prodrug metabolite, undergoes hydrolytic conversion to yield (S)-lactate and (R)-1,3-butanediol in cells

preQ1 with alkyne handle for click chemistry

Chemical Name: N-[6-[[(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]amino]hexyl]-3-(2-propyn-1-yloxy)propanamide
Purity: ≥95% (HPLC)
preQ1 with alkyne handle for click chemistry

Antibiotic

Purity: ≥90% (HPLC)
Antibiotic

pan-DUB activity-based probe with alkyne click handle

Chemical Name: 4-(1-Cyanopyrrolidine-3-carbonyl)-N-[(4-ethynylphenyl)methyl]-1-methylpyrrole-2-carboxamide
Purity: ≥98% (HPLC)
pan-DUB activity-based probe with alkyne click handle

DC-SIGN ligand used to target dendritic cells

Chemical Name: N-(4-(((2R,3S,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenethyl)pent-4-ynamide
Purity: ≥98% (HPLC)
DC-SIGN ligand used to target dendritic cells.

Ionizable cationic lipid

Chemical Name: 2-[2,2-Di-[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine
Purity: ≥95% (HPLC)
Ionizable cationic lipid

Forms monovalent ion channels in lipid bilyers; antifungal

Chemical Name: (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-Amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
Purity: ≥90% (HPLC)
Forms monovalent ion channels in lipid bilyers; antifungal

PreQ1 with biotin handle for RNA labeling and purification

Chemical Name: N-(6-(((2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)amino)hexyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
Purity: ≥95% (HPLC)
PreQ1 with biotin handle for RNA labeling and purification
(3)

Broad spectrum cysteine reactive probe; suitable for live-cell applications

Alternate Names: N-Acryloylindole-alkyne,NAIA-5
Chemical Name: N-5-Hexyn-1-yl-2-[[1-(1-oxo-2-propen-1-yl)-1H-indol-5-yl]oxy]acetamide
Purity: ≥95% (HPLC)
Application of NAIA in HepG2 cells.
(4)

Photosensitizer for proximity labeling experiments, Alkyne reactive group

Chemical Name: 3-(Hex-5-yn-1-yl)-10-methylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
Purity: ≥95% (HPLC)
Photosensitizer for proximity labeling experiments, Alkyne reactive group
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