α-Cyclodextrin
Tocris Bioscience, part of Bio-Techne | Catalog # 3180
Cyclic complexing agent
Product Description
α-Cyclodextrin (α-CD) is a cylindrical oligosaccharide presenting a hydrophilic surface and a lipophilic cavity. α-Cyclodextrin can form inclusion complexes with a diverse range of hydrophobic compounds. These complexes increase the aqueous solubility, dissolution rate, and bioavailability of the guest compounds.Product Specifications
Molecular Weight
972.85
Formula
C36H60O30
Storage
Store at RT
Purity
≥98% (HPLC)
CAS Number
10016-20-3
PubChem ID
444913
InChI Key
HFHDHCJBZVLPGP-RWMJIURBSA-N
SMILES
C(O)[C@@H]1[C@@]2([C@H](O)[C@@H](O)[C@](O1)(O[C@@]3([C@@H](CO)O[C@@]([C@H](O)[C@H]3O)(O[C@@]4([C@@H](CO)O[C@@]([C@H](O)[C@H]4O)(O[C@]5([C@H](O)[C@@H](O)[C@@](O[C@]6([C@H](O)[C@@H](O)[C@@](O[C@]7([C@H](O)[C@@H](O)[C@@](O2)(O[C@@H]7CO)[H])[H])(O[C@@H]6CO)[H])[H])(O[C@@H]5CO)[H])[H])[H])[H])[H])[H])[H])[H]
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 97.28 | 100 | |
| DMSO | 97.28 | 100 |
Preparing Stock Solutions
for α-Cyclodextrin
The following data is based on the product molecular weight 972.85
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.03 mL | 5.14 mL | 10.28 mL |
| 5 mM | 0.21 mL | 1.03 mL | 2.06 mL |
| 10 mM | 0.10 mL | 0.51 mL | 1.03 mL |
| 50 mM | 0.02 mL | 0.10 mL | 0.21 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Rodriguez-Aller New prostaglandin analog formulation for glaucoma treatment containing cyclodextrins for improved stability, solubility and ocular tolerance. Eur.J.Pharm.Biopharm. 2015 PMID: 25960331
Product Specific Notices for α-Cyclodextrin
For research use only
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