(RS)-2-Hydroxyglutaric acid disodium salt
Tocris Bioscience, part of Bio-Techne | Catalog # 6122
Metabolite
Product Description
(RS)-2-Hydroxyglutaric acid disodium salt is an oncometabolite with R- and S- enantiomers overproduced in the neurometabolic disease 2-hydroxyglutaric aciduria (2-HGA).Product Specifications
Molecular Weight
192.08
Formula
C5H6Na2O5
Storage
Store at -20°C
Chemical Name
(RS)-2-Hydroxypentanedioic acid disodium salt
CAS Number
40951-21-1
PubChem ID
134081824
InChI Key
DZHFTEDSQFPDPP-UHFFFAOYSA-L
SMILES
OC(C(O[Na])=O)CCC(O[Na])=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 19.21 | 100 |
Preparing Stock Solutions
for (RS)-2-Hydroxyglutaric acid disodium salt
The following data is based on the product molecular weight 192.08
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.21 mL | 26.03 mL | 52.06 mL |
| 5 mM | 1.04 mL | 5.21 mL | 10.41 mL |
| 10 mM | 0.52 mL | 2.60 mL | 5.21 mL |
| 50 mM | 0.10 mL | 0.52 mL | 1.04 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Du and Hu The roles of 2-Hydroxyglutarate. Front.Cell Dev.Biol. 2021 PMID: 33842477
Product Specific Notices for (RS)-2-Hydroxyglutaric acid disodium salt
For research use only
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