Human/Mouse/Rat NKX2.2 Alexa Fluor™ Plus 555-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB8167AFP555

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FAB8167AFP555-100UG
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Immunocytochemistry

Label

Alexa Fluor Plus 555 (Excitation = 558 nm, Emission = 572 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 883411

View all NKX2.2 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human NKX2.2

Specificity

Detects human NKX2.2 in ELISA and Western Blot.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications

Application
Recommended Usage

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: NKX2.2

NKX2.2, also known as NKX2-2 or NKX2B, is an approximately 30 kDa, 273 amino acid homeobox nuclear transcription factor of the NKX2 protein family. It specifies differentiation of pancreatic islet cells such as alpha, beta, PP, and epsilon lineages.  It also functions in developmental neuronal patterning of the ventral spinal cord in response to graded Sonic Hedgehog gradients and contributes pathfinding of commissural neurons. Within the region used as an immunogen, human NKX2.2 shares 96% and 97% amino acid sequence identity with mouse and rat NKX2.2, respectively.

Long Name

NK2 Homeobox 2

Alternate Names

NKX2B

Entrez Gene IDs

4821 (Human); 18088 (Mouse); 366214 (Rat)

Gene Symbol

NKX2-2

UniProt

O95096 (Human)

Additional NKX2.2 Products

Product Documents

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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