CRTAC1: Proteins and Enzymes

CRTAC1 (cartilage acidic protein 1; also CEP-68) is a 95-105 kDa member of a novel family of EGF domain-containing proteins. It is secreted by articular chondrocytes and may play a role in either cartilage matrix organization, or cell-matrix adhesion. Mature human CRTAC1 is 634 amino acids (aa) in length. It contains four FG-GAP (PheGly-GlyAlaPro) domains (aa 46-437) and one EGF-like motif (aa 559-605). Multiple splice forms exist. There are two alternate start sites at Met9 and Met211 that may ...