Bradykinin RB2/BDKRB2: Small Molecules and Peptides
BDKR2B, a 7TM receptor for the peptide bradykinin, is predominantly expressed on endothelial cells and smooth muscle cells. It plays a key role in the regulation of blood pressure by promoting vasodilation and vascular permeability. BDKR2B heterodimerization with angiotensin II receptors enhances angiotensin II responsiveness. Polymorphisms of BDKR2B are associated with hypertension, cardiovascular risk, and diabetic nephropathy.
3 results for "Bradykinin RB2/BDKRB2 Small Molecules and Peptides" in Products
3 results for "Bradykinin RB2/BDKRB2 Small Molecules and Peptides" in Products
Bradykinin RB2/BDKRB2: Small Molecules and Peptides
BDKR2B, a 7TM receptor for the peptide bradykinin, is predominantly expressed on endothelial cells and smooth muscle cells. It plays a key role in the regulation of blood pressure by promoting vasodilation and vascular permeability. BDKR2B heterodimerization with angiotensin II receptors enhances angiotensin II responsiveness. Polymorphisms of BDKR2B are associated with hypertension, cardiovascular risk, and diabetic nephropathy.
Endogenous agonist at bradykinin receptors (B2 > B1)
| Purity: | ≥95% (HPLC) |
Potent and selective B2 antagonist
| Alternate Names: | Icatibant |
| Purity: | ≥95% (HPLC) |
Bradykinin B2 antagonist
| Chemical Name: | (S)-4-[2-[Bis(cyclohexylamino)methyleneamino]-3-(2-naphthalenyl)-1-oxopropylamino]benzyl tributyl phosphonium chloride hydrochloride |
