22 results for "5-HT1B" in Products

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5-HT1B Products

5-HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5-HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythym light responsiveness, and trigeminal-mediated nociception. It is an important pharmacologic target in the treatment of migrane headaches.

SB 216641 hydrochloride
Catalog #: 1242
(1)
Citations (6)
Product Documents
Images (1)

Selective h5-HT1B antagonist

Chemical Name:
N-[3-[3-(Dimethylamino)ethoxy]-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxamide hydrochloride
Purity:
≥98%
Selective h5-HT1B antagonist
Catalog #
Availability
Size / Price
Qty
1242/50
1242/10
Bulk Order

5-HT1B Antibody - BSA Free
Catalog #: NB100-56350
Citations (3)
Product Documents
Images (5)
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB
Western Blot: 5-HT1B Antibody [NB100-56350]
(5)
Catalog #
Availability
Size / Price
Qty
NB100-56350
NB100-56350SS
Bulk Order

GR 55562 dihydrochloride
Catalog #: 1054
(1)
Citations (11)
Product Documents
Images (1)

5-HT1B antagonist

Chemical Name:
3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamide dihydrochloride
Purity:
≥98%
5-HT1B antagonist
Catalog #
Availability
Size / Price
Qty
1054/10
1054/50
Bulk Order

Human 5-HT1B (NP_000854) VersaClone cDNA
Catalog #: RDC0284
Citations (1)
Product Documents
Images (1)
Reactivity:
Human
R&D Systems VersaClone cDNA Plasmids
Catalog #
Availability
Size / Price
Qty
RDC0284
Bulk Order

CP 93129 dihydrochloride
Catalog #: 1032
(3)
Citations (17)
Product Documents
Images (1)

5-HT1B agonist

Chemical Name:
1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one dihydrochloride
5-HT1B agonist
Catalog #
Availability
Size / Price
Qty
1032/10
1032/50
Bulk Order

NPPB
Catalog #: 0593
(1)
Citations (70)
Product Documents
Images (1)

Inhibits calcium-sensitive chloride currents

Chemical Name:
5-Nitro-2-(3-phenylpropylamino)benzoic acid
Purity:
≥98%
Inhibits calcium-sensitive chloride currents
Catalog #
Availability
Size / Price
Qty
0593/50
Bulk Order

CP 94253 hydrochloride
Catalog #: 1317
(1)
Citations (10)
Product Documents
Images (1)

Potent and selective 5-HT1B agonist

Chemical Name:
5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride
Purity:
≥98%
Potent and selective 5-HT1B agonist
Catalog #
Availability
Size / Price
Qty
1317/50
1317/10
Bulk Order

GR 127935 hydrochloride
Catalog #: 1477
Citations (10)
Product Documents
Images (1)

Potent and selective 5-HT1B and 5-HT1D antagonist

Chemical Name:
N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide hydrochloride
Purity:
≥98%
Potent and selective 5-HT1B and 5-HT1D antagonist
Catalog #
Availability
Size / Price
Qty
1477/10
1477/50
Bulk Order

CGS 12066B dimaleate
Catalog #: 0638
Citations (8)
Product Documents
Images (1)

5-HT1B agonist

Chemical Name:
7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]-quinoxaline dimaleate
Purity:
≥98%
5-HT1B agonist
Catalog #
Availability
Size / Price
Qty
0638/10
0638/50
Bulk Order

Anpirtoline hydrochloride
Catalog #: 0703
Citations (7)
Product Documents
Images (1)

Highly potent 5-HT1B agonist; also 5-HT3 antagonist

Chemical Name:
6-Chloro-2-[piperidinyl-4-thio]pyridine hydrochloride
Purity:
≥99%
Highly potent 5-HT1B agonist; also 5-HT3 antagonist
Catalog #
Availability
Size / Price
Qty
0703/10
0703/50
Bulk Order

RU 24969 hemisuccinate
Catalog #: 0912
(1)
Citations (2)
Product Documents
Images (1)

5-HT1A and 5-HT1B agonist

Chemical Name:
5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate
Purity:
≥99%
5-HT1A and 5-HT1B agonist
Catalog #
Availability
Size / Price
Qty
0912/10
0912/50
Bulk Order

Cyanopindolol hemifumarate
Catalog #: 0993
Citations (11)
Product Documents
Images (1)

5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist

Chemical Name:
4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate
Purity:
≥98%
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
Catalog #
Availability
Size / Price
Qty
0993/10
0993/50
Bulk Order

SB 224289 hydrochloride
Catalog #: 1221
(1)
Citations (12)
Product Documents
Images (1)

Selective 5-HT1B antagonist

Chemical Name:
1'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine hydrochloride
Purity:
≥95%
Selective 5-HT1B antagonist
Catalog #
Availability
Size / Price
Qty
1221/50
1221/10
Bulk Order

Serotonin hydrochloride
Catalog #: 3547
(1)
Citations (93)
Product Documents
Images (1)

Endogenous 5-HT receptor agonist

Alternate Names:
5-Hydroxytryptamine,5-HT
Chemical Name:
3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride
Purity:
≥98%
Endogenous 5-HT receptor agonist
Catalog #
Availability
Size / Price
Qty
3547/50
Bulk Order

SB 699551
Catalog #: 3188
Citations (13)
Product Documents
Images (1)

Selective 5-ht5a antagonist

Chemical Name:
N-[2-(Dimethylamino)ethyl]-N-[[4'-[[(2-phenylethyl)amino]methyl][1,1'-biphenyl]-4-yl]methyl]cyclopentanepropanamide dihydrochloride
Purity:
≥98%
Selective 5-ht5a antagonist
Catalog #
Availability
Size / Price
Qty
3188/50
3188/10
Bulk Order

Sumatriptan succinate
Catalog #: 3586
(1)
Citations (10)
Product Documents
Images (1)

5-HT1A, 5-HT1B and 5-HT1D agonist

Alternate Names:
GR 43175
Chemical Name:
3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate
Purity:
≥99%
5-HT1A, 5-HT1B and 5-HT1D agonist
Catalog #
Availability
Size / Price
Qty
3586/10
3586/50
Bulk Order

Astemizole
Catalog #: 3489
(1)
Citations (13)
Product Documents
Images (1)

Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker

Alternate Names:
Hismanal
Chemical Name:
1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine
Purity:
≥98%
Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker
Catalog #
Availability
Size / Price
Qty
3489/50
Bulk Order

PNU 142633
Catalog #: 1985
Citations (45)
Product Documents
Images (1)

Highly selective 5-HT1D agonist

Chemical Name:
(1S)-1-[2-[4-[4-(Aminocarbonyl)phenyl]-1-piperazinyl]ethyl]-3,4-dihydro-N-methyl-1H-2-benzopyran-6-carboxamide
Purity:
≥98%
Highly selective 5-HT1D agonist
Catalog #
Availability
Size / Price
Qty
1985/10
Bulk Order

5-HT1B Antibody - BSA Free
Catalog #: NBP2-86927
Product Documents
Images (1)
Reactivity:
Human
Details:
Rabbit Polyclonal
Applications:
WB
Western Blot: 5-HT1B Antibody [NBP2-86927]
Catalog #
Availability
Size / Price
Qty
NBP2-86927
Bulk Order

5-HT1B Antibody - BSA Free
Catalog #: NBP3-06662
Product Documents
Images (2)
Reactivity:
Human
Details:
Rabbit Polyclonal
Applications:
IHC
Immunohistochemistry-Paraffin: 5-HT1B Antibody - BSA Free [NBP3-06662]
(2)
Catalog #
Availability
Size / Price
Qty
NBP3-06662
Bulk Order

5-HT1B Overexpression Lysate
Catalog #: NBL1-11775
Product Documents
Images (1)
Reactivity:
Human
Applications:
WB
Western Blot: 5-HT1B Overexpression Lysate [NBL1-11775]
Catalog #
Availability
Size / Price
Qty
NBL1-11775
Bulk Order

5-HT1B Antibody
Catalog #: NBP3-12375
Product Documents
Images (1)
Reactivity:
Human, Mouse, Rat
Details:
Rabbit Polyclonal
Applications:
WB, ELISA, IP
Novus Antibodies
Catalog #
Availability
Size / Price
Qty
NBP3-12375
Bulk Order
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