Serotonin hydrochloride

Name: Serotonin hydrochloride
Brand: Tocris Bioscience
SKU: 3547
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 3547

(1)

Citations (83)

COA / SDS

Endogenous 5-HT receptor agonist

Key Product Details

Description:	Endogenous 5-HT receptor agonist
Alternative Names:	5-Hydroxytryptamine,5-HT
Chemical Name:	3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	212.68

View Full Technical Details for Serotonin hydrochloride

Technical Data
Citations / Reviews (1)

Biological Activity for Serotonin hydrochloride

Serotonin hydrochloride is an endogenous agonist at 5-HT receptors and endogenous substrate for 5-HT transporters. Neurotransmitter that has roles in regulation of mood, emesis, sexuality, sleep and appetite in vivo.

Technical Data for Serotonin hydrochloride

M. Wt	212.68
Formula	C₁₀H₁₂N₂O.HCl
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	153-98-0
PubChem ID	160436
InChi Key	MDIGAZPGKJFIAH-UHFFFAOYSA-N
Smiles	NCCC2=CNC1=CC=C(O)C=C12.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Serotonin hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	21.27	100
	DMSO	21.27	100

Preparing Stock Solutions for Serotonin hydrochloride

The following data is based on the product molecular weight 212.68.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.70 mL	23.51 mL	47.02 mL
5 mM	0.94 mL	4.70 mL	9.40 mL
10 mM	0.47 mL	2.35 mL	4.70 mL
50 mM	0.09 mL	0.47 mL	0.94 mL

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Reconstitution Calculator

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References for Serotonin hydrochloride

References are publications that support the biological activity of the product.

Barnes and Sharp A review of central 5-HT receptors and their function. Neuropharmacology 1999 PMID: 10462127