PNU 142633

Tocris Bioscience, part of Bio-Techne | Catalog # 1985

Highly selective 5-HT1D agonist
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1985/10
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Key Product Details

Description

Highly selective 5-HT1D agonist

View all 5-HT1D Receptor Agonists »

Product Description

PNU 142633 is a very selective, high affinity 5-HT1D receptor agonist (Ki values are 6 and > 18000 nM at human 5-HT1D and 5-HT1B receptors respectively). Inhibits sympathetically-induced tachycardic responses and blocks neurogenic plasma protein extravasation in vivo.

Product Specifications

Molecular Weight

422.53

Formula

C24H30N4O3

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(1S)-1-[2-[4-[4-(Aminocarbonyl)phenyl]-1-piperazinyl]ethyl]-3,4-dihydro-N-methyl-1H-2-benzopyran-6-carboxamide

CAS Number

187665-65-2

PubChem ID

9845148

InChI Key

PNTVCCRNJOGKGA-QFIPXVFZSA-N

SMILES

O=C(NC)C3=CC(CCO2)=C(C=C3)[C@@H]2CCN1CCN(C4=CC=C(C(N)=O)C=C4)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 42.25 100

Preparing Stock Solutions for PNU 142633

The following data is based on the product molecular weight 422.53

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.37 mL 11.83 mL 23.67 mL
5 mM 0.47 mL 2.37 mL 4.73 mL
10 mM 0.24 mL 1.18 mL 2.37 mL
50 mM 0.05 mL 0.24 mL 0.47 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for PNU 142633

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PNU 142633

For research use only

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