CP 94253 hydrochloride
Catalog # 1317 | Tocris Bioscience a Bio-Techne Brand
Potent and selective 5-HT1B agonist
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Key Product Details
Description: | Potent and selective 5-HT1B agonist |
Chemical Name: | 5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 293.8 |
Citations for CP 94253 hydrochloride (7)
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Citations are publications that use Bio-Techne products. Selected citations for CP 94253 hydrochloride include:
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Gadgaard & Jensen
(2020)
Functional characterization of 5-HT1A and 5-HT1B serotonin receptor signaling through G-protein-activated inwardly rectifying K+ channels in a fluorescence-based membrane potential assay.
Biochem Pharmacol.
175
PMID: 32088264 -
Mansari et al.
(2015)
Effects of acute and sustained administration of Vort. on the serotonin system in the hippocampus: electrophysiological studies in the rat brain.
Neuron.
232:2343
PMID: 25665528 -
Doslikova et al.
(2013)
5-HT2C receptor agonist anorectic efficacy potentiated by 5-HT1B receptor agonist coapplication: an effect mediated via increased proportion of pro-opiomelanocortin neurons activated.
J Neurosci.
33:9800
PMID: 23739976 -
Eriksson et al.
(2013)
Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11.
Psychopharmacology (Berl).
18:1096
PMID: 23032875 -
Hagan et al.
(2012)
5-HT(1B) autoreceptor regulation of serotonin transporter activity in synaptosomes.
Synapse.
66:1024
PMID: 22961814 -
McDevitt et al.
(2011)
Serotonin 1B autoreceptors originating in the caudal dorsal raphe nucleus reduce expression of fear and depression-like behavior.
Pain.
69:780
PMID: 21353664 -
Heisler et al.
(2006)
Serotonin reciprocally regulates melanocortin neurons to modulate food intake.
Biol Psychiatry.
51:239
PMID: 16846858
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