CP 93129 dihydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 1032
5-HT1B agonist
Product Description
CP 93129 dihydrochloride is a potent and highly selective 5-HT1B agonist (Ki values are 8.1, 1100, 1500, 2900 and 7200 nM for 5-HT1B, 5-HT1D, 5-HT1A, 5-HT1c and 5-HT2, respectively). Reduces food intake and decreases body weight in rats.Licensing Information
Sold for research purposes under agreement from Pfizer Inc.Product Specifications
Molecular Weight
288.18
Formula
C12H13N3O.2HCl
Storage
Desiccate at RT
Chemical Name
1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one dihydrochloride
CAS Number
879089-64-2
PubChem ID
46927988
InChI Key
FLVJHUZZKVJQNH-UHFFFAOYSA-N
SMILES
Cl.Cl.O=C1NC2=C(NC=C2C2=CCNCC2)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 28.82 | 100 | |
| DMSO | 28.82 | 100 |
Preparing Stock Solutions
for CP 93129 dihydrochloride
The following data is based on the product molecular weight 288.18
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.47 mL | 17.35 mL | 34.70 mL |
| 5 mM | 0.69 mL | 3.47 mL | 6.94 mL |
| 10 mM | 0.35 mL | 1.74 mL | 3.47 mL |
| 50 mM | 0.07 mL | 0.35 mL | 0.69 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Koe Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253. Drug Development Research
- Hamid Modulation of neurotransmission by GPCRs is dependent upon the microarchitecture of the primed vesicle complex. J Neurosci. 2014 PMID: 24381287
- Lee Infusion of the serotonin1B (5-HT1B) agonist CP-93,129 into the parabrachial nucleus potently and selectively reduces food intake in rats. Psychopharmacology 1998 PMID: 9566817
Product Specific Notices for CP 93129 dihydrochloride
For research use only
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