Mouse Mrc2 Alexa Fluor® 594-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # AF4789T
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Immunogen
Ala31-Ala1413
Accession # AAI16643
Specificity
Clonality
Host
Isotype
Applications for Mouse Mrc2 Alexa Fluor® 594-conjugated Antibody
Western Blot
Formulation, Preparation, and Storage
Purification
Formulation
Shipping
Stability & Storage
Background: Mrc2
Mrc2 (macrophage mannose receptor 2; also uPARAP/Endo180) is a 180 kDa member of the mannose receptor family. It is found on fibroblasts, macrophages and endothelial cells. Mrc2 binds and internalizes glycoproteins plus collagen types I and IV. Mouse Mrc2 is a type I transmembrane glycoprotein that is 1479 amino acids (aa) in length. It possesses a 1383 aa extracellular domain (ECD) (aa 31‑1479) and a short 45 aa cytoplasmic tail. The ECD contains eight C‑type lectin domains plus one fibronectin type II domain (aa 181‑229) that binds collagen. There are two splice variants, one which shows an eight aa substitution for aa 173‑1479, and a second that shows a 72 aa substitution for aa 982‑1479. Over aa 311‑413, mouse Mrc2 shares 91% and 97% aa identity with human and rat Mrc2, respectively.
Long Name
Alternate Names
Gene Symbol
UniProt
Additional Mrc2 Products
Product Documents for Mouse Mrc2 Alexa Fluor® 594-conjugated Antibody
Product Specific Notices for Mouse Mrc2 Alexa Fluor® 594-conjugated Antibody
This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.
For research use only