Species Reactivity:

Mouse

Immunogen:

Mouse myeloma cell line NS0-derived recombinant mouse Mrc2
Ala31-Ala1413
Accession # AAI16643

Applications:

Western Blot

Label:

Alexa Fluor 750 (Excitation=749 nm, Emission=775 nm)

Specificity:

Detects mouse Mrc2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross‑reactivity with recombinant human Mrc2 is observed.

View Full Technical Details for Mouse Mrc2 Alexa Fluor® 750-conjugated Antibody

Technical Data
Citations / Reviews

Applications for Mouse Mrc2 Alexa Fluor® 750-conjugated Antibody

	Recommended Concentration	Sample
Western Blot	Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application.

Formulation, Preparation and Storage

Purification	Antigen Affinity-purified
Formulation	Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

=

Mass (in vial)

÷

Desired Reconstitution Concentration

Background: Mrc2

Mrc2 (macrophage mannose receptor 2; also uPARAP/Endo180) is a 180 kDa member of the mannose receptor family. It is found on fibroblasts, macrophages and endothelial cells. Mrc2 binds and internalizes glycoproteins plus collagen types I and IV. Mouse Mrc2 is a type I transmembrane glycoprotein that is 1479 amino acids (aa) in length. It possesses a 1383 aa extracellular domain (ECD) (aa 31‑1479) and a short 45 aa cytoplasmic tail. The ECD contains eight C‑type lectin domains plus one fibronectin type II domain (aa 181‑229) that binds collagen. There are two splice variants, one which shows an eight aa substitution for aa 173‑1479, and a second that shows a 72 aa substitution for aa 982‑1479. Over aa 311‑413, mouse Mrc2 shares 91% and 97% aa identity with human and rat Mrc2, respectively.

Item	Value
Long Name	Mannose Receptor, C-type 2
Entrez Gene IDs	9902 (Human); 17534 (Mouse); 498011 (Rat)
Alternate Names	CD280, CD280 antigen, CD280C-type mannose receptor 2, CLEC13E, CLEC13EUPAR-associated protein, ENDO180C-type lectin domain family 13 member E, Endo180, Endocytic receptor 180, KIAA0709FLJ35911, Macrophage mannose receptor 2, Mrc2, UPARAPendocytic receptor (macrophage mannose receptor family), Urokinase receptor-associated protein, Urokinase-type plasminogen activator receptor-associated protein, mannose receptor, C type 2, uPARAP, urokinase plasminogen activator receptor-associated protein

Customer Reviews for Mouse Mrc2 Alexa Fluor® 750-conjugated Antibody

There are currently no reviews for this product. Be the first to review Mouse Mrc2 Alexa Fluor® 750-conjugated Antibody and earn rewards!

Have you used Mouse Mrc2 Alexa Fluor® 750-conjugated Antibody?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review

Product Documents for Mouse Mrc2 Alexa Fluor® 750-conjugated Antibody

Product Datasheets

Download Product Datasheets

Mouse Mrc2 Alexa Fluor® 750-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # AF4789S

Key Product Details