CXCL1/GRO alpha/KC/CINC-1 Antibody (251021) [mFluor Violet 610 SE]
Novus Biologicals, part of Bio-Techne | Catalog # FAB515MFV610
Conjugate
Catalog #
Key Product Details
Species Reactivity
Rat
Applications
Western Blot, Neutralization
Label
mFluor Violet 610 SE (Excitation = 421 nm, Emission = 613 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # 251021
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant rat CXCL1/GRO alpha/KC/CINC‑1
Ala25-Lys96
Accession # P14095
Ala25-Lys96
Accession # P14095
Specificity
Detects rat CXCL1/GRO alpha/KC/CINC‑1 in direct ELISAs and Western blots. In Western blots, 100% cross-reactivity with recombinant human (rh) GRO alpha, rhGRO beta, rhGRO gamma, and recombinant mouse KC is observed. No cross-reactivity with recombinant rat (rr) CINC2a, rrCXCL3, rhCXCL5, 6, 7, 8, 9, 10, 11, 12 or 13, rmCXCL2, 6, 9, 10, 12, 13, or recombinant porcine CXCL8 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Applications for CXCL1/GRO alpha/KC/CINC-1 Antibody (251021) [mFluor Violet 610 SE]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Neutralization
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: CXCL1/GRO alpha/KC/CINC-1
CXCL1/GRO alpha/KC/CINC-1 is an ELR+ angiogenic chemokine that interacts with CXCR2/IL-8 RB to attract and activate neutrophils. It is produced at sites of microbial infection by macrophages, monocytes, Kupffer cells, hepatocytes, endothelial and epithelial cells, cardiac and vascular smooth muscle cells, fibroblasts, melanocytes, mast cells, and neurons. CXCL1 function is associated with the development and extent of atherosclerosis, Alzheimer’s disease, and tumor angiogenesis.
Alternate Names
CINC-1, CINC1, GRO alpha, KC, MGSA-alpha
Gene Symbol
CXCL1
Additional CXCL1/GRO alpha/KC/CINC-1 Products
Product Documents for CXCL1/GRO alpha/KC/CINC-1 Antibody (251021) [mFluor Violet 610 SE]
Product Specific Notices for CXCL1/GRO alpha/KC/CINC-1 Antibody (251021) [mFluor Violet 610 SE]
mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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