Key Product Details

Species Reactivity

Rat

Applications

Neutralization, Western Blot

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 251021

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CXCL1/GRO alpha/KC/CINC-1 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant rat CXCL1/GRO alpha/KC/CINC‑1
Ala25-Lys96
Accession # P14095

Specificity

Detects rat CXCL1/GRO alpha/KC/CINC‑1 in direct ELISAs and Western blots. In Western blots, 100% cross-reactivity with recombinant human (rh) GRO alpha, rhGRO beta, rhGRO gamma, and recombinant mouse KC is observed. No cross-reactivity with recombinant rat (rr) CINC2a, rrCXCL3, rhCXCL5, 6, 7, 8, 9, 10, 11, 12 or 13, rmCXCL2, 6, 9, 10, 12, 13, or recombinant porcine CXCL8 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for CXCL1/GRO alpha/KC/CINC-1 Antibody (251021) [FITC]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Neutralization

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CXCL1/GRO alpha/KC/CINC-1

CXCL1/GRO alpha, also known as KC in mouse and CINC-1 in rat, is a member of the CXC family of chemokines. Human CXCL1/GRO alpha is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 57% and 59% amino acid sequence identity with the human protein, respectively. Genome-wide analysis suggests that the protein encoded by the mouse Cxcl3 gene is homologous to human CXCL1/GRO alpha protein. Human CXCL1/GRO alpha can be cleaved into three isoforms CXCL1/GRO alpha (aa 4-73), CXCL1/GRO alpha (aa 5-73), and CXCL1/GRO alpha (aa 6-73) which show higher activity than the full length protein. CXCL1/GRO alpha is secreted by mast cells and macrophages whereupon it acts as a chemoattractant for neutrophils.

Alternate Names

CINC-1, CINC1, GRO alpha, KC, MGSA-alpha

Gene Symbol

CXCL1

Additional CXCL1/GRO alpha/KC/CINC-1 Products

Product Documents for CXCL1/GRO alpha/KC/CINC-1 Antibody (251021) [FITC]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CXCL1/GRO alpha/KC/CINC-1 Antibody (251021) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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