TIMP-3 Products
TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.
115 results for "TIMP-3" in Products
115 results for "TIMP-3" in Products
TIMP-3 Products
TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Source: | NS0 |
| Accession #: | P35625 |
| Applications: | InhibAct |
Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #183551 |
| Applications: | WB, IHC, IP |
| Reactivity: | Human, Mouse, Rat, Canine, Bovine, +1 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF, Flow |
![Immunohistochemistry-Paraffin: TIMP-3 Antibody [NBP2-29478]](https://resources.bio-techne.com/images/products/TIMP-3-Antibody-Immunohistochemistry-Paraffin-NBP2-29478-img0008.jpg "Immunohistochemistry-Paraffin: TIMP-3 Antibody [NBP2-29478]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
| Reactivity: | Human, Mouse, Rat, Canine, Bovine, +1 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF, Flow, CyTOF-ready |
![Immunohistochemistry-Paraffin: TIMP-3 Antibody - Azide and BSA Free [NBP2-33098]](https://resources.bio-techne.com/images/products/TIMP-3-Antibody-Azide-and-BSA-Free-Immunohistochemistry-Paraffin-NBP2-33098-img0002.jpg "Immunohistochemistry-Paraffin: TIMP-3 Antibody - Azide and BSA Free [NBP2-33098]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #277128 |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #277128 |
| Applications: | IP, CyTOF-reported, ICFlow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #277128 |
| Applications: | ICFlow |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #183551 |
| Applications: | WB, IHC, IP, ELISA(Cap), ELISA(Det) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #183551 |
| Applications: | WB, IHC, IP, ELISA(Cap), ELISA(Det) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #183551 |
| Applications: | WB, IHC, IP, ELISA(Cap), ELISA(Det) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #183551 |
| Applications: | WB, IHC, IP, ELISA(Cap), ELISA(Det) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #183551 |
| Applications: | WB, IHC, IP, ELISA(Cap), ELISA(Det) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #183551 |
| Applications: | WB, IHC, IP, ELISA(Cap), ELISA(Det) |