22 results for "P2X Receptor Antagonists Small Molecules and Peptides" in Products
P2X Receptor Antagonists: Small Molecules and Peptides
P2X Purinergic Receptor Subunits
Each functional P2X receptor is formed from either three identical subunits (homomeric) or a combination of two or three different subunits (heteromeric). Except for P2X6, all subunits can form homomeric receptors, however, P2X7 subunits only form homomeric receptors. Functional receptors are named for their constituent subunits, for example a homomeric receptor composed of P2X7 subunits is called a P2X7 receptor, while a heteromeric receptor composed of P2X2 ...
Competitive P2X7 antagonist
| Chemical Name: | 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride |
| Purity: | ≥98% (HPLC) |
Highly selective P2X1 antagonist
| Chemical Name: | 4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid, octasodium salt |
| Purity: | ≥90% (HPLC) |
Potent and selective P2X7 antagonist
| Chemical Name: | N-[1-[[(Cyanoamino)(5-quinolinylamino)methylene]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide |
| Purity: | ≥97% (HPLC) |
Non-selective P2 antagonist
| Chemical Name: | Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid tetrasodium salt |
Potent and selective P2X antagonist
| Chemical Name: | 2',3'-O-(2,4,6-Trinitrophenyl)adenosine-5'-triphosphate tetra(triethylammonium) salt |
| Purity: | ≥95% (HPLC) |
Non-selective P2X antagonist
| Chemical Name: | Pyridoxalphosphate-6-azophenyl-2',5'-disulfonic acid tetrasodium salt |
Non-selective P2 antagonist
| Chemical Name: | 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt |
| Purity: | ≥98% (HPLC) |
Non-competitive P2X7 antagonist
| Chemical Name: | 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl] phenyl isoquinolinesulfonic acid ester |
| Purity: | ≥98% (HPLC) |
Potent and selective P2X4 antagonist
| Chemical Name: | 5-(3-Bromophenyl)-1,3-dihydro-2H-benzofuro[3,2-e]-1,4-diazepin-2-one |
| Purity: | ≥98% (HPLC) |
Selective P2X4 allosteric antagonist
| Chemical Name: | N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea |
| Purity: | ≥98% (HPLC) |
Selective P2X4 antagonist
| Chemical Name: | N-[3-(Aminosulfonyl)-4-(3-chlorophenoxy)phenyl]benzeneacetamide |
| Purity: | ≥98% (HPLC) |
Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist
| Chemical Name: | 6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)bis[4-amino- 5-hydroxy-1,3-naphthalenedisulphonic acid] tetrasodium salt |
| Purity: | ≥90% (HPLC) |
Selective P2Y11 and P2X1 antagonist
| Chemical Name: | 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-fluoro-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt |
| Purity: | ≥90% (HPLC) |
Potent P2X7 antagonist
| Chemical Name: | N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective human P2X7 antagonist
| Chemical Name: | 3-[1-[[(3'-Nitro[1,1'-biphenyl]-4-yl)oxy]methyl]-3-(4-pyridinyl)propyl]-2,4-thiazolidinedione |
| Purity: | ≥98% (HPLC) |
Selective and competitive P2X1 antagonist
| Chemical Name: | 8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid, hexasodium salt |
Potent and selective P2X7 antagonist; brain penetrant
| Chemical Name: | 2-(Phenylthio)-N-[[tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-yl]methyl-3-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective P2X7 antagonist
| Chemical Name: | N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine |
| Purity: | ≥98% (HPLC) |
Potent P2X3 antagonist
| Chemical Name: | 4,4',4'',4'''-[Carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakisbenzenesulfonic acid tetrasodium salt |
| Purity: | ≥90% (HPLC) |
Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive
| Chemical Name: | 5-[[[(3-Phenoxyphenyl)methyl][(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]carbonyl]-1,2,4-benzenetricarboxylic acid disodium salt |
| Purity: | ≥98% (HPLC) |
Selective P2X3 and P2X2/3 antagonist
| Chemical Name: | 5-[[4,5-Dimethoxy-2-(methylethyl)phenyl]methyl]-2,4-pyrimidinediamine |
| Purity: | ≥98% (HPLC) |
Potent and selective P2X1 antagonist
| Chemical Name: | 8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt |
| Purity: | ≥95% (HPLC) |
