Suramin hexasodium salt

Tocris Bioscience, part of Bio-Techne | Catalog # 1472

Non-selective P2 antagonist
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Key Product Details

Description

Non-selective P2 antagonist

View all P2X Receptor Antagonists »

Product Description

Suramin hexasodium salt is a non-selective P2 purinergic antagonist. Also blocks calmodulin binding to recognition sites and G protein coupling to G protein-coupled receptors. Increases open probability of ryanodine receptor (RyR) channels and acts as a competitive α1β2γ2 GABAA receptor antagonist. Anticancer, antiviral and antiparasitic agent.

This product may be supplied with a high degree of hydration and some residual NaCl, the amounts of which are batch dependent. Please refer to the Certificate of Analysis to obtain the batch specific Net Product Content.

Product Specifications

Molecular Weight

1429.15

Formula

C51H34N6Na6O23S6

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt

CAS Number

129-46-4

PubChem ID

5360

InChI Key

VAPNKLKDKUDFHK-UHFFFAOYSA-H

SMILES

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].CC1=CC=C(C=C1NC(=O)C1=CC=CC(NC(=O)NC2=CC=CC(=C2)C(=O)NC2=C(C)C=CC(=C2)C(=O)NC2=C3C(C=C(C=C3S([O-])(=O)=O)S([O-])(=O)=O)=C(C=C2)S([O-])(=O)=O)=C1)C(=O)NC1=C2C(C=C(C=C2S([O-])(=O)=O)S([O-])(=O)=O)=C(C=C1)S([O-])(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 50
DMSO 5

Preparing Stock Solutions for Suramin hexasodium salt

The following data is based on the product molecular weight 1429.15

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.35 mM 2.00 mL 10.00 mL 19.99 mL
1.75 mM 0.40 mL 2.00 mL 4.00 mL
3.5 mM 0.20 mL 1.00 mL 2.00 mL
17.5 mM 0.04 mL 0.20 mL 0.40 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Suramin hexasodium salt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Suramin hexasodium salt

For research use only

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