mAChR M1 Antagonists Products

M₁ receptors are members of the G-protein-coupled receptor (GPCR) family which are found mostly bound to G_q proteins. They are one of five muscarinic receptors that act to control the metabotropic functions of acetylcholine (ACh) in the central nervous system (CNS). M₁ receptors are most densely populated in the neuronal cells of the cerebral cortex and hippocampus. Activation of the M₁ receptor leads to several responses, including the upregulation of phospholipase C, the activation of ion ...