AP1M1: Proteins and Enzymes

AP1M1, or AP-1 complex subunit mu-1, contains two similarly massed isoforms that are 49 kDa and 50 kDa, and is involved in the binding of clathrin to coated vesicle receptors within the Golgi vesicle. Kaposi's sarcoma, immunodeficiency, neuronitis, and malaria are being used in research along with AP1M1 to determine the relationship between the protein and disease. Pathways including the adaptive immune system, lysosome vesicle biogenesis, and trans-Golgi Network Vesicle Budding are linked to the protein, as are proteins such as HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, and HIST1H4E.