L-690,488

Name: L-690,488
Brand: Tocris Bioscience
SKU: 0682

Tocris Bioscience, part of Bio-Techne | Catalog # 0682

Citations (3)

COA / SDS

Cell permeable prodrug of the IMPase inhibitor L-690,330 (Cat. No. 0681)

Discontinued Product

0682 has been discontinued. View all Inositol Lipid Inhibitors products.

Key Product Details

Description:	Cell permeable prodrug of the IMPase inhibitor L-690,330 (Cat. No. 0681)
Chemical Name:	1-[(4-Hydroxyphenoxy)ethylidene]bis[phosphinylidynebis(oxymethylene)]-2,2-dimethylpropanoate
Purity:	≥98% (HPLC)
Molecular Weight:	754.7

View Full Technical Details for L-690,488

Technical Data
Citations

Biological Activity for L-690,488

L-690,488 is a cell-permeable prodrug of the potent inositol monophosphatase inhibitor L-690,330 (Cat. No. 0681); penetrates cells more effectively than its metabolite.

Licensing Information

Sold with the permission of Merck Sharp and Dohme Ltd.

Technical Data for L-690,488

M. Wt	754.7
Formula	C₃₂H₅₂O₁₆P₂
Storage	Store at -80°C
Purity	≥98% (HPLC)
CAS Number	142523-14-6
PubChem ID	5132514
InChi Key	LOTSPVPQHAUHCE-UHFFFAOYSA-N
Smiles	OC1=CC=C(OC(P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)(C)P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for L-690,488

References are publications that support the biological activity of the product.

Chen Stimulatory effect of Li on glucose transport in rat adipocytes is not mediated by elevation of IP₁. Am.J.Physiol. 1998 PMID: 9688629
Atack Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers. J.Pharmacol.Exp.Ther. 1994 PMID: 8035344