INF 39

Tocris Bioscience, part of Bio-Techne | Catalog # 6341

Irreversible NLRP3 inhibitor
Discontinued Product
6341 has been discontinued. View all Inflammasomes Inhibitors products.

Key Product Details

Description

Irreversible NLRP3 inhibitor

View all Inflammasomes Inhibitors »

Product Description

INF 39 is an irreversible NLRP3 inhibitor (exhibits 52% inhibition of NLRP3 ATPase at 100 μM). Inhibits IL-1β release, caspase activation and pyroptosis in THP-1 cells. Reduces inflammation in a rat colitis model. Exhibits low cytotoxicity.

Product Specifications

Molecular Weight

224.68

Formula

C12H13ClO2

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

Ethyl 2-(2-chlorobenzyl)acrylate

CAS Number

866028-26-4

PubChem ID

69150705

InChI Key

VTAOWWAFBSFWSG-UHFFFAOYSA-N

SMILES

CCOC(C(CC1=C(C=CC=C1)Cl)=C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble in DMSO (supplied pre-dissolved in DMSO, 10mg/ml)

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Background References

References are publications that support the biological activity of the product.

Product Documents for INF 39

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for INF 39

For research use only

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