CP 471474

Tocris Bioscience, part of Bio-Techne | Catalog # 3780

Broad spectrum MMP inhibitor
Discontinued Product
3780 has been discontinued. View all Matrix Metalloprotease (MMP) Inhibitors products.

Key Product Details

Description

Broad spectrum MMP inhibitor

View all Matrix Metalloprotease (MMP) Inhibitors »

Product Description

CP 471474 is a broad spectrum MMP inhibitor (IC50 values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Attenuates early left ventricular dilation after experimental myocardial infarction in mice.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Product Specifications

Molecular Weight

368.38

Formula

C16H17FN2O5S

Storage

Store at -20°C

Purity

≥97% (HPLC)

Chemical Name

2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide

CAS Number

210755-45-6

PubChem ID

9907286

InChI Key

QCOQJYRPDUMCNP-UHFFFAOYSA-N

SMILES

FC1=CC=C(OC2=CC=C(S(NC(C)(C)C(NO)=O)(=O)=O)C=C2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 36.84 100

Preparing Stock Solutions for CP 471474

The following data is based on the product molecular weight 368.38

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.71 mL 13.57 mL 27.15 mL
5 mM 0.54 mL 2.71 mL 5.43 mL
10 mM 0.27 mL 1.36 mL 2.71 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Calculators

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Reconstitution Calculator

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Product Documents for CP 471474

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CP 471474

For research use only

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