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Mouse Abeta 42 ELISA Kit (Colorimetric)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-50033

Novus Biologicals, part of Bio-Techne
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NBP3-50033

Key Product Details

Sample Type & Volume Required Per Well

Serum, plasma and other biological fluids (100 uL)

Sensitivity

1.88 pg/mL

Assay Range

3.13 - 200 pg/mL

Product Specifications

Assay Type

Sandwich ELISA

Kit Type

ELISA Kit (Colorimetric)

Reactivity

Mouse

Specificity

This kit recognizes Mouse Abeta 42 in samples. No significant cross-reactivity or interference between Mouse Abeta 42 and analogues was observed

Description

Assay Length: 3 h 30 min

Precision

Intra-Assay Precision (Precision within an assay) CV% < 10

Inter-Assay Precision (Precision between assays) CV% < 10

Recovery for Mouse Abeta 42 ELISA Kit (Colorimetric)

Recovery

80 - 120%

Linearity

Mouse Abeta 42 ELISA Kit (Colorimetric)

Scientific Data Images for Mouse Abeta 42 ELISA Kit (Colorimetric)

Mouse Abeta 42 ELISA Kit (Colorimetric)

ELISA: Mouse Abeta 42 ELISA Kit (Colorimetric) [NBP3-50033]

Standard Curve Reference.

Kit Contents for Mouse Abeta 42 ELISA Kit (Colorimetric)

  • Biotinylated Detection Ab Diluent
  • Certificate of Analysis
  • Concentrated Biotinylated Detection Ab (100x)
  • Concentrated HRP Conjugate (100x)
  • Concentrated Wash Buffer (25x)
  • HRP Conjugate Diluent
  • Micro ELISA Plate (Dismountable)
  • Plate Sealer
  • Product Description
  • Reference Standard
  • Reference Standard & Sample Diluent
  • Stop Solution
  • Substrate Reagent

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Abeta 42

Amyloid beta-protein (Abeta) is associated with neuronal injury and death in Alzheimer's disease. The most common isoforms are of Amyloid beta are Abeta40 and Abeta42.

The Amyloid beta proteins function as a cell surface receptor and supports neurite growth, neuronal adhesion and axonogenesis on the surface of neurons. Amyloid betas are also involved in cell mobility functions and transcription regulation via various protein-protein interactions.

Mutations in Amyloid Precursor Protein (APP) that are associated with early-onset Alzheimer's have been shown to specifically increase the relative production of the Abeta42 isoform. Abeta 42 is also more fibrillogenic and plays a bigger role in deneurogeneration. It is therefore more strongly associated with Alzheimer's disease than Abeta 40.

Abeta42 antibodies are useful tools for Alzheimer's studies and research on amyloid plaques.

Alternate Names

Amyloid beta 42, Beta-amyloid protein 42

Gene Symbol

APP

Additional Abeta 42 Products

Product Documents for Mouse Abeta 42 ELISA Kit (Colorimetric)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mouse Abeta 42 ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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