Mouse Adenosine A2b R (NP_031439) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC2227

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RDC2227
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Key Product Details

Species

Mouse

Accession Number

NP_031419

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Adenosine A2b R

The Adenosine A2b Receptor (ADORA2B) gene codes for a receptor located on chromosome 17 (near the Smith-Magenis syndrome region) that initiates adenylyl cyclase in the presence of adenosine. The encoded adenoside receptor is 332 amino acids long, around 36 kDA, and is member to the G protein-coupled receptor superfamily and interacts with netrin-1 to promote axon elongation. ADORA2B has been associated with cholera, hepatitis B, breast cancer, carcinoma, eclampsia, ischemia, asthma, cystic fibrosis, astrocytoma, and atherosclerosis. It is involved in signal transduction IP3 signaling, GPCR ligand binding and signaling, and the methotrexate pathway through interactions with the EZR, NTN1, ADA, DDC, and SLC9A3R2 genes.

Long Name

Adenosine A2b Receptor

Alternate Names

Adenosine A2bR, ADORA2B

Entrez Gene IDs

136 (Human); 11541 (Mouse); 29316 (Rat)

Gene Symbol

ADORA2B

UniProt

NP_031419

Additional Adenosine A2b R Products

Product Documents for Mouse Adenosine A2b R (NP_031439) VersaClone cDNA

Product Datasheets

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Product Specific Notices for Mouse Adenosine A2b R (NP_031439) VersaClone cDNA

For research use only

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