Human GluR5/GRIK1 (NP_000821) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC0944

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Key Product Details

Species

Human

Accession Number

NP_000821

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: GluR5/GRIK1

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brain stem whereas the four epsilon subunits display limited distribution.

Long Name

Glutamate Receptor 5

Alternate Names

EAA3, EEA3, GluK1, GRIK1

Entrez Gene IDs

2897 (Human); 14805 (Mouse); 29559 (Rat)

Gene Symbol

GRIK1

UniProt

NP_000821

Additional GluR5/GRIK1 Products

Product Documents for Human GluR5/GRIK1 (NP_000821) VersaClone cDNA

Product Datasheets

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Product Specific Notices for Human GluR5/GRIK1 (NP_000821) VersaClone cDNA

For research use only

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