Human Collagen XVII (NP_000485) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC1658

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Key Product Details

Species

Human

Accession Number

NP_000485

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Collagen XVII

Collagen XVII encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Long Name

Collagen Type XVII Alpha 1

Alternate Names

BP180, BPA-2, BPAG2, COL17A1, ERED, LAD-1

Entrez Gene IDs

1308 (Human); 12821 (Mouse); 294027 (Rat)

Gene Symbol

COL17A1

UniProt

NP_000485

Additional Collagen XVII Products

Product Documents for Human Collagen XVII (NP_000485) VersaClone cDNA

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Product Specific Notices for Human Collagen XVII (NP_000485) VersaClone cDNA

For research use only

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