STK38 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27552

Novus Biologicals, part of Bio-Techne
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NBP2-27552
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Predicted:

Bovine (100%), Canine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all NDR1/STK38 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KPTVATSNHPET corresponding to C-Terminus (near) according to NP_009202.1.

Specificity

This antibody is NOT expected to cross-react with STK38L (GeneID 23012).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

Novus Biologicals Goat STK38 Antibody (NBP2-27552) is a polyclonal antibody validated for use in WB and ELISA. Anti-STK38 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for STK38 Antibody

Western Blot: STK38 Antibody [NBP2-27552]

Western Blot: STK38 Antibody [NBP2-27552]

Western Blot: STK38 Antibody [NBP2-27552] - NBP2-27552 (0.5ug/ml) staining of Human Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for STK38 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

0.5 - 2 ug/ml
Application Notes
WB: Approx. 55 kDa band observed in human and rat spleen lysates (calculated MW of 54.2 kDa band according to NP_009202.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NDR1/STK38

STK38 belongs to the NDR family of serine/threonine protein kinases. NDR kinases require the phosphorylation of conserved Ser/Thr residues for activation. NDR family members have two unique stretches of primary sequence: an N-terminal regulatory (NTR) domain and an insert of several residues between subdomains VII and VIII of the kinase domain. The kinase domain insert functions as an auto-inhibitory sequence (AIS), while binding of the co-activator MOB (Mps-one binder) proteins to the NTR domain releases NDR kinases from inhibition of autophosphorylation. STK38 negatively regulates the activation of MEKK1/2 by direct interaction with the catalytic domain of MEKK1/2. The negative regulation of MEKK1/2 is not due to its phosphorylation by STK38.

Long Name

Nuclear Dbf2-related Kinase 1

Alternate Names

STK38

Entrez Gene IDs

361813 (Rat)

Gene Symbol

STK38

UniProt

NP_009202.1 (Human)

Additional NDR1/STK38 Products

Product Documents for STK38 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for STK38 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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