SIGNR1/CD209b Antibody [DyLight 488]
Novus Biologicals, part of Bio-Techne | Catalog # AF1836K
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot, Adhesion Blockade
Label
DyLight 488 (Excitation = 493 nm, Emission = 518 nm)
Antibody Source
Polyclonal Goat IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse SIGNR1
Ser76-Gly325
Accession # Q8CJ91
Ser76-Gly325
Accession # Q8CJ91
Specificity
Detects mouse SIGNR1 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross‑reactivity with recombinant mouse (rm) SIGNR3 and rmSIGNR4 is observed, and approximately 10% cross-reactivity with recombinant human DC-SIGNR and rmDC‑SIGN is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for SIGNR1/CD209b Antibody [DyLight 488]
Application
Recommended Usage
Adhesion Blockade
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: SIGNR1/CD209b
Mouse SIGNR1 is a type II transmembrane protein that is a homolog of human DCSIGN (R). It is a C-type lectin expressed by marginal zone macrophages and by medullary and subcapsular macrophages in lymph nodes. SIGN R1 binds and mediates the uptake of dextran via mannose and fucose binding sites.
Long Name
SIGN-related 1
Alternate Names
CD209b
Gene Symbol
Cd209a
Additional SIGNR1/CD209b Products
Product Documents for SIGNR1/CD209b Antibody [DyLight 488]
Product Specific Notices for SIGNR1/CD209b Antibody [DyLight 488]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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