Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

DyLight 755 (Excitation = 754 nm, Emission = 776 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PGC1 beta Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 50 and 100 of human peroxisome proliferator-activated receptor gamma coactivator 1 beta using the numbering given in entry NP_573570.2 (GeneID 133522).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for PGC-1 beta Antibody [DyLight 755]

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PGC1 beta

PGC-1 beta is a tissue specific co-activator that enhances the activity of estrogen receptor alpha. The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner. PGC-1 beta is also involved in activation of nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. Ectopic expression of this protein has been shown to lead to increased mitochondrial numbers and basal oxygen consumption.

Long Name

Peroxisome Proliferator-activated Receptor gamma, Coactivator 1 beta

Alternate Names

ERRL1, PERC, PPARGC1B

Gene Symbol

PPARGC1B

Additional PGC1 beta Products

Product Documents for PGC-1 beta Antibody [DyLight 755]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PGC-1 beta Antibody [DyLight 755]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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