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Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Alexa Fluor 594 (Excitation = 590 nm, Emission = 617 nm)

Antibody Source

Polyclonal Goat IgG

Product Specifications

Immunogen

E. coli-derived recombinant mouse DMBT1
Trp215-Gly420
Accession # Q60997

Specificity

Detects mouse DMBT1 in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse DMBT1 Alexa Fluor® 594-conjugated Antibody

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: DMBT1

DMBT1 (Deleted in malignant brain tumor-1; also MUCLIN, Hensin, CRP-Ductin, and gp300/350) is a 230‑350 kDa member of the DMBT1 family of molecules. It is expressed by select cell types, including macrophages, intestinal epithelium, and pancreatic acinar cells. DMBT1 is both transmembrane (TM) and secreted, and possesses multiple activities that may be predicated on multimerization. It drives epithelial differentiation, binds Gm+ and Gm- bacteria, and associates with cytoskeletal actin. Mouse DMBT1 is a type I TM glycoprotein 2085 amino acids (aa) in length. Its extracellular region contains eight SRCR repeats (aa 31‑980, plus 1510‑1610), five CUB domains (aa 1023‑1490, plus 1633‑1742), and a ZP segment (aa 1751‑1999). Multiple splice variants exist. There are deletions of aa 584‑733, 397‑534, 593‑731 and, 2032‑2085 (within the TM segment), plus an insertion of 11 aa after Asp29. Over aa 215‑420, mouse DMBT1 shares 75% aa identity with human DMBT1.

Long Name

Deleted in Malignant Brain Tumors 1

Alternate Names

CRP-ductin, Ebnerin, GP340, Hensin, Muclin, SAG, Vomeroglandin

Entrez Gene IDs

1755 (Human); 12945 (Mouse); 170568 (Rat)

Gene Symbol

DMBT1

UniProt

Additional DMBT1 Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Mouse DMBT1 Alexa Fluor® 594-conjugated Antibody


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

For research use only

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