Mouse CD39L2/ENTPD6 Alexa Fluor™ Plus 647-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB6288AFP647

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FAB6288AFP647-100UG
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Key Product Details

Species Reactivity

Mouse

Applications

Immunohistochemistry, Immunocytochemistry

Label

Alexa Fluor Plus 647 (Excitation = 658 nm, Emission = 675 nm)

Antibody Source

Monoclonal Rat IgG2B Clone # 774308

View all CD39L2/ENTPD6 Antibodies »

Product Specifications

Immunogen

Chinese Hamster Ovary cell line, CHO-derived mouse CD39L2/ENTPD6

Specificity

Detects mouse CD39L2/ENTPD6 in direct ELISA.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2B

Applications

Application
Recommended Usage

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CD39L2/ENTPD6

CD39L2, also known as ectonucleoside triphosphate diphosphohydrolase-6 (ENTPD-6) and NTPDase-6, is a nucleoside phosphohydrolase of the CD39 family of enzymes that is present on the surface of cells (1). This Type II membrane protein also exists as a soluble, secreted protein. CD39L2 displays a preference for the nucleoside-5’-diphosphates GDP and IDP over CDP and UDP (2). Nucleoside-5’-triphosphates are also hydrolyzed, but at much lower rates. CD39L2 is expressed at its highest levels in cardiac muscle and in heart capillary endothelial cells (3). CD39L2 may play a functional role in the regulation and recruitment of platelet activation in the heart. The cytoplasmic and transmembrane domains of rmCD39L2 were replaced with a signal sequence, resulting in the secretion of the recombinant protein.

References

  1. Chadwick, B.P. and A.M. Frischauf (1998) Genomics. 50:357.
  2. Hicks-Berger, C.A. et al. (2000) J.Biol. Chem. 275:34041.
  3. Yeung, G. et al. (2000) Biochemistry. 39:12916.

Long Name

Ecto-Nucleoside Triphosphate Diphosphohydrolase 6

Alternate Names

CD39L2, ENTPD6, NTPD3, NTPDase 6

Entrez Gene IDs

955 (Human); 12497 (Mouse); 85260 (Rat)

Gene Symbol

ENTPD6

UniProt

742115

Additional CD39L2/ENTPD6 Products

Product Documents

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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