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Mouse BTN2A2/Butyrophilin 2A2 Alexa Fluor™ Plus 555-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # AF4917AFP555

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AF4917AFP555-100UG

Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Alexa Fluor Plus 555 (Excitation = 558 nm, Emission = 572 nm)

Antibody Source

Polyclonal Sheep IgG

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse BTN2A2/Butyrophilin 2A2

Specificity

Detects mouse BTN2A2/Butyrophilin 2A2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: BTN2A2/Butyrophilin 2A2

Mouse Butyrophilin 2 (BTN2; also Btn2a2) is a 65‑70 kDa member of the BTN/MOG family of proteins. It is expressed on colonic epithelium and endothelial cells, and marginally on monocytes. The counterreceptor for BTN2 is DC-SIGN and binding is predicated on the presence of BTN2 mannose residues. Mature mouse BTN2 is presumably 487 amino acids (aa) in length. It is a type I transmembrane glycoprotein that potentially contains a 206 aa extracellular domain (ECD) (aa 29‑234). The ECD contains one V-type (aa 52‑129) and one C2-type (aa 152‑234) Ig-like domain. There is one alternative splice variant. It shows a deletion of aa 372‑400 plus a 17 aa substitution for aa 422‑451. Over aa 30‑248, mouse BTN2 shares 70% and 89% aa identity with human and rat BTN2, respectively.

Long Name

Butyrophilin Subfamily 2 Member A2

Alternate Names

BTF2, BTN2, Butyrophilin 2

Entrez Gene IDs

10385 (Human); 238555 (Mouse); 306957 (Rat)

Gene Symbol

BTN2A2

UniProt

Additional BTN2A2/Butyrophilin 2A2 Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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