LIV-1/Zip6 Antibody [ADC] - (Ladiratuzumab Vedotin, Research Grade)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44538

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

ADC

Antibody Source

Monoclonal Human IgG1

Concentration

LYOPH mg/ml

View all LIV-1/Zip6 Antibodies »

Product Specifications

Immunogen

LIV-1/Zip6 (Uniprot: Q13433)

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Theoretical MW

146.96 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

This product is an Antibody-Drug Conjugate (ADC) for Research Use Only (RUO).

Ladiratuzumab Vedotin is an ADC that combines a humanized anti-LIV-1 monoclonal antibody linked to a synthetic cytotoxic cell-disrupting agent, monomethyl auristatin E (MMAE)

This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for LIV-1/Zip6 Antibody [ADC] - (Ladiratuzumab Vedotin, Research Grade)

Hu LIV-1/Zip6 mAb [ADC] - (Ladiratuzumab Vedotin) [NBP3-44538] -

Flow Cytometry: Hu LIV-1/Zip6 mAb [ADC] - (Ladiratuzumab Vedotin) [NBP3-44538] -

Human LIV1 CHOS cells were stained with LIV-1/Zip6 (Ladiratuzumab Vedotin) Antibody and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.07456 ug/mL.
Hu LIV-1/Zip6 mAb [ADC] - (Ladiratuzumab Vedotin) [NBP3-44538] -

Functional: Hu LIV-1/Zip6 mAb [ADC] - (Ladiratuzumab Vedotin) [NBP3-44538] -

The killing ratio LIV-1/Zip6 (Ladiratuzumab Vedotin) Antibody by Human LIV-1 HEK293 Cell Line increased with the increase of antibody concentration, and the killing Rate (%) reached 74%
Hu LIV-1/Zip6 mAb [ADC] - (Ladiratuzumab Vedotin) [NBP3-44538] -

ELISA: Hu LIV-1/Zip6 mAb [ADC] - (Ladiratuzumab Vedotin) [NBP3-44538] -

Immobilized human LIV 1, His Tag at 2 ug/mL can bind LIV-1/Zip6 (Ladiratuzumab Vedotin) Antibody, EC50=0.007652 ug/mL.

Applications for LIV-1/Zip6 Antibody [ADC] - (Ladiratuzumab Vedotin, Research Grade)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

> 90% by SDS-PAGE and HPLC

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in powder form. Store at -80C once reconstituted.

Background: LIV-1/Zip6

Alternate Names

LIV-1, solute carrier family 39 (zinc transporter), member 6, zinc transporter ZIP6

Additional LIV-1/Zip6 Products

Product Documents for LIV-1/Zip6 Antibody [ADC] - (Ladiratuzumab Vedotin, Research Grade)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for LIV-1/Zip6 Antibody [ADC] - (Ladiratuzumab Vedotin, Research Grade)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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