Skip to main content

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor 700 (Excitation = 675-700 nm, Emission = 723 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 396012

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human ST6 Gal Sialytransferase 1/ST6GAL1
Lys27-Cys406
Accession # P15907

Specificity

Detects human ST6 Gal Sialytransferase 1/ST6GAL1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) ST6GAL2, rhST6GALNAC1, or rhST6GALNAC5 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ST6 Gal Sialyltransferase 1/ST6GAL1

ST6GAL1 ( beta-galactoside alpha-2-6 sialyl transferase 1; also alpha-2,6-ST) is a 47-49 kDa member of the glycosyltransferase 29 family of proteins. It is principally expressed in hepatocytes, placenta and skeletal muscle, and may be unique in its ability to generate Sia-alpha -2, 6-Gal structures on liver proteins. Human ST6GAL1 is a 406 amino acid (aa) type II transmembrane protein that resides in Golgi membranes. It contains a short cytoplasmic segment (aa 1-9) and an extended luminal domain
(aa 27‑406) that possesses a phosphorylation site at Tyr369. ST6GAL1 undergoes BACE1-mediated cleavage to generate a 364 aa, 52-53 kDa soluble form. This acts within the Golgi lumen to glycosylate proteins destined for secretion. There is one potential alternative start site at Met232. Over aa 27‑406, human ST6GAL1 shares 75% aa identity with mouse ST6GAL1.

Long Name

ST6 beta-Galactoside alpha-2,6-Sialyltransferase 1

Alternate Names

Alpha 2,6-ST, B-cell antigen CD75, CD75, SIAT1, ST6N

Entrez Gene IDs

6480 (Human); 20440 (Mouse); 25197 (Rat)

Gene Symbol

ST6GAL1

UniProt

Additional ST6 Gal Sialyltransferase 1/ST6GAL1 Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

For research use only

Loading...
Loading...
Loading...