PTP beta/zeta/PTPRZ was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Rat Anti-Human PTP beta/zeta/PTPRZ Monoclonal Antibody (Catalog # MAB26881) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS017) and counterstained with hematoxylin (blue). Specific staining was localized to neuronal cell bodies. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Applications for Human PTP beta/ zeta/PTPRZ Antibody

Application

Recommended Usage

Immunohistochemistry

8-25 µg/mL
Sample:

Immersion fixed paraffin-embedded sections of human brain (cortex)

Reviewed Applications

Read 1 review rated 5 using MAB26881 in the following applications:

Immunohistochemistry (1 Review)

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: PTP beta/zeta/PTPRZ

PTPRZ, also known as Protein tyrosine phosphatase beta/zeta (PTP beta/ zeta), is a member of the receptor-type protein-tyrosine phosphatase family. This phosphatase is involved in the regulation of specific developmental processes in the central nervous system. A protein of 2,307 amino acids, PTPRZ is membrane-spanning with two cytoplasmic protein tyrosine phosphatase domains and an extracellular domain.

Long Name

Protein Tyrosine Phosphatase beta/zeta

Alternate Names

HPTPZ, PTP18, PTPRZ, PTPRZ1, RPTPB

Entrez Gene IDs

5803 (Human)

Gene Symbol

PTPRZ1

UniProt

P23471

Additional PTP beta/zeta/PTPRZ Products

Product Documents for Human PTP beta/ zeta/PTPRZ Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human PTP beta/ zeta/PTPRZ Antibody

For research use only

Citations
Reviews

Human PTP beta/ zeta/PTPRZ Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB26881

Key Product Details

Species Reactivity

Validated:

Cited:

Applications

Validated:

Cited:

Label

Antibody Source

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Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human PTP beta/ zeta/PTPRZ Antibody

PTP beta/ zeta/PTPRZ in Human Brain.