Human Lymphotoxin  beta/TNFSF3 Alexa Fluor™ Plus 488-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB1684AFP488

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FAB1684AFP488-100UG
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 135105

View all Lymphotoxin beta/TNFSF3 Antibodies »

Product Specifications

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Lymphotoxin  alpha/ beta

Specificity

Detects human Lymphotoxin alpha beta heterotrimers in direct ELISAs and Western blots. This antibody detects an epitope in the Lymphotoxin  beta subunit. In direct ELISAs, this antibody does not cross-react with recombinant human (rh) Lymphotoxin  alpha, rhAPRIL, rhBAFF, rhTNF‑ alpha, rhTWEAK, rhEDA‑A2, rhEDA, rhTRAIL, rhVEGI, rhTRANCE, rhFas Ligand, or rhOX40 Ligand.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Lymphotoxin beta/TNFSF3

Lymphotoxin beta is a type II transmembrane protein member of the TNF ligand superfamily and is now designated TNFSF3. Lymphotoxin beta associates with Lymphotoxin alpha to form two types of heterotrimers, Lymphotoxin alpha1 beta2 and Lymphotoxin  alpha2 beta1. Lymphotoxin beta is expressed by activated CD4 T cells, unpolarized IL‑2‑secreting effector T cells, and Th1 effector cells.

Long Name

Lymphotoxin beta

Alternate Names

LTB, TNFSF3

Entrez Gene IDs

4050 (Human); 102135554 (Cynomolgus Monkey)

Gene Symbol

LTB

Additional Lymphotoxin beta/TNFSF3 Products

Product Documents

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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