Human 5-HT2C APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB5764A
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # 496214
Product Specifications
Immunogen
NS0 mouse myeloma cell line transfected with human 5-HT2C
Accession # P28335
Accession # P28335
Specificity
Detects human 5-HT2C in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Human 5-HT2C APC-conjugated Antibody
Detection of 5‑HT2C in HEK293 Human Cell Line Transfected with Human 5-HT2C and eGFP by Flow Cytometry.
HEK293 human embryonic kidney cell line transfected with human 5-HT2C and eGFP was stained with either (A) Mouse Anti-Human 5-HT2C APC-conjugated Monoclonal Antibody (Catalog # FAB5764A) or (B) Mouse IgG2AAllophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.Applications for Human 5-HT2C APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: HEK293 human embryonic kidney cell line transfected with human 5-HT2C and eGFP
Sample: HEK293 human embryonic kidney cell line transfected with human 5-HT2C and eGFP
Spectra Viewer
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectra Viewer
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: 5-HT2C
5-HT2C is a 45 kDa 7TM receptor that belongs to the G-protein coupled receptor #1 family. It binds serotonin and is neuronally expressed in the limbic system of the brain. The release of dopamine due to 5-HT2C ligation regulates mood, appetite, and motivation. 5-HT2C is an important pharmacologic target in the treatment of psychosis, schizophrenia, depression, anxiety, and migrane headaches. Multiple isoforms of 5-HT2C can be generated by RNA editing. Human 5-HT2C shares 89% aa sequence identity with mouse and rat 5-HT2C.
Long Name
5-Hydroxytryptamine Receptor 2C
Alternate Names
5-HTR2C, 5HT2C, HTR2C, Serotonin Receptor 2C
Gene Symbol
HTR2C
UniProt
Additional 5-HT2C Products
Product Documents for Human 5-HT2C APC-conjugated Antibody
Product Specific Notices for Human 5-HT2C APC-conjugated Antibody
For research use only
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