GUCY2C Antibody [ADC] - (Indusatumab Vedotin, Research Grade)

ADC

Monoclonal Human IgG₁

LYOPH mg/ml

Guanylyl Cyclase C/GUCY2C (Uniprot: P25092)

Monoclonal

Human

IgG₁

150.45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

This product is an Antibody-Drug Conjugate (ADC) for Research Use Only (RUO).

Indusatumab vedotin is an antibody-drug conjugate that is under development for the treatment of pancreatic cancer and other gastrointestinal cancers. It consists of a monoclonal antibody (indusatumab) that targets the enzyme guanylate cyclase 2C which is present in some cancers, linked to an average of three to four molecules of the chemotherapeutic agent monomethyl auristatin E (MMAE).

This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

> 90% by SDS-PAGE and HPLC

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

No Preservative

LYOPH mg/ml

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Store at -20C in powder form. Store at -80C once reconstituted.