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CCR3 Antibody (5E8-G9-B4) [Alexa Fluor™ Plus 594] - Chimeric

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81046AFP594

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-81046AFP594

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Alexa Fluor Plus 594

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # 5E8-G9-B4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

CCR3

Specificity

Recognises human CCR3, a chemokine receptor highly expressed of eosinophils, as well as Th2-Tcells, basophils, platelets, mast-cells, mononuclear phagocytes, airway epithelial cells, and hematopoietic progenitor cells (CD34+).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for CCR3 Antibody (5E8-G9-B4) [Alexa Fluor™ Plus 594] - Chimeric

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CCR3

CKR3, or C-C chemokine receptor type 3, is a G protein-coupled, seven-transmembrane domain receptor protein. The chemokine eotaxin appears to be a highly specific agonist for CKR3, making CKR3 one of the factors responsible for selective recruitment of eosinophils to sites of inflammation (1). It has been shown that more than one chemokine activates CKR3, including eotaxin, RANTES, and MCP-3 (2). Since CKR3 is prominently expressed in eosinophils , it has been named the human eosinophil eotaxin receptor (2,3).

Alternate Names

CCR3, CD193

Gene Symbol

CCR3

Additional CCR3 Products

Product Documents for CCR3 Antibody (5E8-G9-B4) [Alexa Fluor™ Plus 594] - Chimeric

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CCR3 Antibody (5E8-G9-B4) [Alexa Fluor™ Plus 594] - Chimeric



This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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