B7-H2/ICOSLG Antibody (BLR166J)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14740

Recombinant Monoclonal Antibody
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NBP3-14740
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit Clone # BLR166J

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all B7-H2 Antibodies »

Product Specifications

Immunogen

between 250 and 300

Clonality

Monoclonal

Host

Rabbit

Scientific Data Images for B7-H2/ICOSLG Antibody (BLR166J)

B7-H2/ICOSLG Antibody (BLR166J)

Western Blot;B7-H2/ICOSLG Antibody (BLR166J)[NBP3-14740]

Western Blot;B7-H2/ICOSLG Antibody (BLR166J) Whole cell lysate (50 µg) from Ramos, MCF-7, HEK293T, and RKO cells prepared using NETN lysis buffer. Antibody: Rabbit anti-ICOSL/B7-H2 recombinant monoclonal antibody used at 1:1000. Secondary: HRP-conjugated goat anti-rabbit IgG . Detection: Chemiluminescence with an exposure time of 3 minutes. Lower Panel: Rabbit anti-COPB2 antibody.

Applications for B7-H2/ICOSLG Antibody (BLR166J)

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

>95%

Formulation

Phosphate Buffered Saline (PBS) containing 0.2% BSA and

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 2 - 8 C / 1 year from date of receipt

Background: B7-H2

B7-RP1 is a 40 kD protein, also known as ICOS ligand, B7-H2, and B7h. It has recently been clustered as CD275. It is a member of the immunoglobulin receptor superfamily expressed on splenic B cells, dendritic cells and macrophages. The expression of this antigen is increased by TNF- alpha stimulation and is highly upregulated by local inflammation. B7RP1 binds to ICOS and co-stimulates T cell and B cell responses. Two isoforms of this protein have been reported to occur as a result of alternative splicing. These isoforms show differential tissue distribution.

Long Name

B7 Homolog 2

Alternate Names

B7H2, B7RP-1, CD275, GL50, ICOSL, ICOSLG

Gene Symbol

ICOSLG

Additional B7-H2 Products

Product Documents for B7-H2/ICOSLG Antibody (BLR166J)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for B7-H2/ICOSLG Antibody (BLR166J)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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