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11 results for "Lipid Metabolism Inhibitors Small Molecules and Peptides" in Products

Lipid Metabolism Inhibitors: Small Molecules and Peptides

When glucose supplies are low, the body is able to draw upon lipids as an alternative energy source. Lipids are generally stored as triglycerides and the first step in lipid metabolism is the conversion to glycerol and fatty acids. Glycerol (dihydroxyacetone phosphate) can enter the glycolysis pathway, and proceed to the Krebs cycle and oxidative phosphorylation. Fatty acids are converted to acetyl CoA, which can directly enter the Krebs cycle and subsequently oxidative phosphorylation. Each ...

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Diacylglycerol lipase inhibitor

Alternate Names: U 57908
Chemical Name: O,O'-[1,6-Hexanediylbis(iminocarbonyl)]dioxime cyclohexanone
Purity: ≥95% (HPLC)
Diacylglycerol lipase inhibitor

Cell permeable inhibitor of SREBP activation

Chemical Name: 4-[4-(4-Methylphenyl)-2-thiazolyl]-2-propylpyridine hydrobromide
Purity: ≥97% (HPLC)
Cell permeable inhibitor of SREBP activation

Selective fatty acid desaturase 2 inhibitor

Chemical Name: α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile
Purity: ≥95% (HPLC)
Selective fatty acid desaturase 2 inhibitor

Inhibitor of phosphatidylcholine transfer protein (PC-TP)

Chemical Name: 2,4-Dichloro-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]carbonyl]benzamide
Purity: ≥98% (HPLC)
Inhibitor of phosphatidylcholine transfer protein (PC-TP)

2,3-Oxidosqualene cyclase (OSC) inhibitor; blocks cholesterol synthesis

Chemical Name: (4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone
Purity: ≥98% (HPLC)
2,3-Oxidosqualene cyclase (OSC) inhibitor; blocks cholesterol synthesis

Potent acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor

Chemical Name: 1,4-Dihydro-1'-[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4'-piperidin]-7(6H)-one
Purity: ≥98% (HPLC)
Potent acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor

Potent fatty acid synthase inhibitor; proapoptotic

Alternate Names: trans-C 75
Chemical Name: (2R*,3S*)-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid
Purity: ≥94% (HPLC)
Potent fatty acid synthase inhibitor; proapoptotic

Competitive inhibitor of SREBP site 1 protease

Chemical Name: 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide dihydrochloride
Purity: ≥97% (HPLC)
Competitive inhibitor of SREBP site 1 protease

Potent microsomal triglyceride transfer protein (MTP) inhibitor

Chemical Name: N-(2,2,2-Trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide methanesulfonate
Purity: ≥98% (HPLC)
Potent microsomal triglyceride transfer protein (MTP) inhibitor

Potent and reversible fatty acid desaturase 1 inhibitor; orally bioavailable

Chemical Name: N-[2-[[3,4-Dihydro-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]thio]ethyl]acetamide
Purity: ≥98% (HPLC)
Potent and reversible fatty acid desaturase 1 inhibitor; orally bioavailable

SCD-1 inhibitor

Alternate Names: NSC 14613
Chemical Name: 4-Pyridinecarboxylic acid 2-phenylhydrazide
Purity: ≥99% (HPLC)
SCD-1 inhibitor
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