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52 results for "Compounds for Stem Cell Differentiation" in Products

Compounds for Stem Cell Differentiation Products

DMSO, sterile filtered, wide ranging applications in cell culture, cryopreservation and organic chemistry. Solvent for polar and nonpolar compounds

Alternate Names: Methyl sulfoxide
Chemical Name: Dimethyl sulfoxide
Purity: ≥99.9%
DMSO, sterile filtered, wide ranging applications in cell culture, cryopreservation and organic chemistry. Solvent for polar and nonpolar compounds

γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling

Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester
Purity: ≥99% (HPLC)
Using DAPT to differentiate hiPSCs into dopaminergic neurons
(2)

Adenylyl cyclase activator

Alternate Names: Coleonol,Colforsin
Chemical Name: (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
Purity: ≥98% (HPLC)
Adult Stem Cell-derived Liver Organoids
(2)

Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs

Alternate Names: LDN 193189 2HCl
Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥98% (HPLC)
Application of LDN 193189 in motor neurons differentiated from iPSCs
(2)

Intracellular cryoprotective agent

Chemical Name: Dimethyl sulfoxide
Purity: ≥99.9%
Intracellular cryoprotective agent

DAPT synthesized to Ancillary Material Grade

Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenylglycine 1,1-dimethylethyl ester
Purity: ≥99%
DAPT synthesized to Ancillary Material Grade

High affinity PKC activator; also APP modulator

Chemical Name: (2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide
Purity: ≥98% (HPLC)
High affinity PKC activator; also APP modulator

PDE inhibitor (non-selective)

Chemical Name: 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
Purity: ≥98% (HPLC)
PDE inhibitor (non-selective)

Endogenous retinoic acid receptor agonist

Alternate Names: Tretinoin,ATRA
Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid
Purity: ≥98% (HPLC)
iPSC differentiation with retinoic acid
(2)

Anti-inflammatory glucocorticoid

Chemical Name: (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione
Purity: ≥98% (HPLC)
Anti-inflammatory glucocorticoid

Synthetic retinoid; induces differentiation of stem cells

Chemical Name: 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoic acid
Purity: ≥99% (HPLC)
Synthetic retinoid; induces differentiation of stem cells

Selective ALK2 inhibitor

Chemical Name: 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
Purity: ≥98% (HPLC)
Selective ALK2 inhibitor

Glutathione (GSH) precursor; maintains stem cell function in culture.

Chemical Name: (2R)-2-Acetamido-3-sulfanylpropanoic acid
Purity: ≥98% (HPLC)
Adult Stem Cell-derived Lung Organoids
(5)

Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation

Chemical Name: 3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenol
Purity: ≥97% (HPLC)
Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation

Potent AMPK inhibitor; also BMP type I receptor inhibitor

Alternate Names: Compound C,BML-275
Chemical Name: 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride
Purity: ≥98% (HPLC)
Potent AMPK inhibitor; also BMP type I receptor inhibitor

Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells

Chemical Name: O-(4-Hydroxy-3-iodophenyl-3,5-diiodo-L-tyrosine
Purity: ≥98% (HPLC)
Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells

Endogenous agonist of LPA1 and LPA2

Chemical Name: 1-O-9Z-Octadecenoyl-sn-glyceryl-3-phosphoric acid sodium salt
Endogenous agonist of LPA1 and LPA2

Retinoic acid synthesized to Ancillary Material Grade

Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E-nonatetraenoic acid
Purity: ≥98%
Retinoic acid synthesized to Ancillary Material Grade

Smo receptor agonist

Chemical Name: 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine
Purity: ≥98% (HPLC)
applications of purmorphamine in neurons derived from hiPSCs
(2)

LDN 193189 synthesized to cGMP guidelines

Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥99%
LDN 193189 synthesized to cGMP guidelines

Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs

Chemical Name: 2-(Dihydrogen phosphate)-L-ascorbic acid sodium salt
Purity: ≥95% (HPLC)
Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs

Tankyrase (AKA PARP5) inhibitor; used to generate neurons from epiblast stem cells

Chemical Name: N-(Cyclopropylmethyl)-4-(4-methoxybenzoyl)-N-[(3,5,7,8-tetrahydro-4-oxo-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl]-1-piperidineacetamide
Purity: ≥98% (HPLC)
Tankyrase (AKA PARP5) inhibitor; used to generate neurons from epiblast stem cells

Selective JNK inhibitor

Chemical Name: Anthra[1-9-cd]pyrazol-6(2H)-one
Purity: ≥98% (HPLC)
Selective JNK inhibitor

FGFR1 and -3 inhibitor

Chemical Name: N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
Purity: ≥98% (HPLC)
FGFR1 and -3 inhibitor

AMPK activator

Chemical Name: N1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide
Purity: ≥99% (HPLC)
AMPK activator
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