2-Phospho-L-ascorbic acid trisodium salt
Tocris Bioscience, part of Bio-Techne | Catalog # 5778
Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs
Key Product Details
Description
Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs
Product Description
2-Phospho-L-ascorbic acid trisodium salt is a stable ascorbic acid derivative used in cell culture; in combination with FGF-2, maintains differentiation potential in bone marrow-derived mesenchymal stem cells (MSC) through increased expression of HGF. Also exhibits synergistic protection of hMSCs under oxidative stress in combination with N-acetylcysteine (Cat. No. 5619).Product Specifications
Molecular Weight
322.05
Formula
C6H6Na3O9P
Storage
Desiccate at RT
Purity
≥95% (HPLC)
Chemical Name
2-(Dihydrogen phosphate)-L-ascorbic acid sodium salt
CAS Number
66170-10-3
PubChem ID
10990876
InChI Key
VWCFDYSMDMCPLU-OFBPEYICSA-K
SMILES
[O-]C([C@]([C@@H](O)CO)([H])O1)=C(OP([O-])([O-])=O)C1=O.[Na+].[Na+].[Na+]
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 32.2 | 100 |
Preparing Stock Solutions
for 2-Phospho-L-ascorbic acid trisodium salt
The following data is based on the product molecular weight 322.05
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.11 mL | 15.53 mL | 31.05 mL |
| 5 mM | 0.62 mL | 3.11 mL | 6.21 mL |
| 10 mM | 0.31 mL | 1.55 mL | 3.11 mL |
| 50 mM | 0.06 mL | 0.31 mL | 0.62 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Bae L-ascorbic acid 2-phosphate and fibroblast growth factor-2 treatment maintains differentiation potential in bone marrow-derived mesenchymal stem cells through expression of hepatocyte growth factor. Growth Factors 2015 PMID: 25714612
- Li Synergistic protection of N-acetylcysteine and ascorbic acid 2-phosphate on human mesenchymal stem cells against mitoptosis, necroptosis and apoptosis. Sci.Rep. 2015 PMID: 25909282
- Falcon An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors. PLoS One 2014 PMID: 25210890
Product Specific Notices for 2-Phospho-L-ascorbic acid trisodium salt
For research use only
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