alpha-1B Adrenergic R/ADRA1B: Small Molecules and Peptides
ADRA1B, also known as the alpha-1B-adrenergic receptor, is a 7TM catecholamine receptor with selectivity for epinephrine and norepinephrine. ADRA1B functions in diverse settings including vasoconstriction and myocardial contractility, neuronal dopaminergic responses, dendritic cell migration and inflammatory responses, and neuroendocrine regulation of fertility.
20 results for "alpha-1B Adrenergic R/ADRA1B Small Molecules and Peptides" in Products
20 results for "alpha-1B Adrenergic R/ADRA1B Small Molecules and Peptides" in Products
alpha-1B Adrenergic R/ADRA1B: Small Molecules and Peptides
ADRA1B, also known as the alpha-1B-adrenergic receptor, is a 7TM catecholamine receptor with selectivity for epinephrine and norepinephrine. ADRA1B functions in diverse settings including vasoconstriction and myocardial contractility, neuronal dopaminergic responses, dendritic cell migration and inflammatory responses, and neuroendocrine regulation of fertility.
α1 agonist
| Chemical Name: | (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride |
| Purity: | ≥98% (HPLC) |
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
| Chemical Name: | 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine |
| Purity: | ≥98% (HPLC) |
Dopamine antagonist with some D4 selectivity; also 5-HT2A/2C antagonist
| Chemical Name: | 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine |
| Purity: | ≥98% (HPLC) |
Selective α1 agonist
| Chemical Name: | 2-(2-Cyclopropylphenoxymethyl)imidazoline hydrochloride |
| Purity: | ≥98% (HPLC) |
GluN2B-selective NMDA antagonist
| Chemical Name: | (αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate |
| Purity: | ≥98% (HPLC) |
Adrenergic α receptor antagonist; antihypertensive
| Chemical Name: | 3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]phenol methanesulfonate |
| Purity: | ≥98% (HPLC) |
5-HT2 antagonist; also D2 antagonist; atypical antipsychotic
| Alternate Names: | ICI 204,636 |
| Chemical Name: | 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate |
| Purity: | ≥98% (HPLC) |
α1 and α2B antagonist; also MT3 antagonist
| Chemical Name: | 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine hydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
| Chemical Name: | 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone |
| Purity: | ≥99% (HPLC) |
α2 agonist. Also I1 ligand
| Chemical Name: | 2-[(2,6-Dichlorophenyl)amino-2-imidazoline hydrochloride |
| Purity: | ≥98% (HPLC) |
α1 antagonist; PGK1 activator
| Chemical Name: | 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-piperazine hydrochloride |
| Purity: | ≥98% (HPLC) |
Dopamine antagonist; displays some D2 selectivity
| Chemical Name: | 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone hydrochloride |
| Purity: | ≥98% (HPLC) |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% (HPLC) |
Potent and non-selective β antagonist; also potent α1 antagonist
| Alternate Names: | BM 14190 |
| Chemical Name: | 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol |
| Purity: | ≥98% (HPLC) |
Selective α1A antagonist
| Chemical Name: | 5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective α2 antagonist
| Chemical Name: | 6-Chloro-N-methyl-2,3,4,5-tetrahydro-1-H-3-benzazepine hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective 5-HT1A agonist
| Alternate Names: | TVX Q 7821 |
| Chemical Name: | 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3(2H)-one-1,1-dioxide |
| Purity: | ≥99% (HPLC) |
5-HT4 agonist; stimulates intestinal ACh release
| Alternate Names: | R 51619 |
| Chemical Name: | (±)-4-Amino-5-chloro-N-[1-[(3R*,4S*)-3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide |
| Purity: | ≥99% (HPLC) |
Highly selective α1 antagonist
| Alternate Names: | BE 2254 |
| Chemical Name: | 2-{[β-(4-Hydroxyphenyl)ethyl]aminomethyl}-1-tetralone hydrochloride |
| Purity: | ≥98% (HPLC) |
α1 antagonist
| Alternate Names: | UK 33274 |
| Chemical Name: | 4-Amino-2-[4-(1,4-benzodioxan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazoline methanesulfonate |
| Purity: | ≥98% (HPLC) |
